Results 81 to 90 of about 5,445 (212)

Accelerated and intensified manufacturing of an adenovirus‐vectored vaccine to enable rapid outbreak response

Biotechnology and Bioengineering, Volume 121, Issue 1, Page 176-191, January 2024.
Abstract The Coalition for Epidemic Preparedness Innovations' “100‐day moonshot” aspires to launch a new vaccine within 100 days of pathogen identification, followed by large‐scale vaccine availability within the “second hundred days.” Here, we describe work to optimize adenoviral vector manufacturing for rapid response, by minimizing time to clinical ...
Carina C. D. Joe, Rameswara R. Segireddy, Cathy Oliveira, Adam Berg, Yuanyuan Li, Dimitrios Doultsinos, Steffi Scholze, Asma Ahmad, Piergiuseppe Nestola, Julia Niemann, Alexander D. Douglas   +10 more
wiley   +1 more source

Research of external signs, microscopy and chemical composition of juglans regia l. partitions

Сеченовский вестник, 2018
Objective: to study the microscopy, external signs of walnut partitions and the chemical composition of the alcohol extract from this type of raw material.Materials and methods. Microscopy was prepared by the pharmacopoeial method.
N. V. Chebyshev, L. O. Martemyanova, A. V. Streliaeva, D. I. Lezhava, R. M. Kuznetsov   +4 more
doaj  

Quantitation Methods of Thermopsis Alkaloids: A Review

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. The major alkaloids of Thermopsis lanceolata R. Br. herb are thermopsine (N-methylcytisine), pachycarpine, and anagyrine, while the seeds predominantly contain cytisine used to treat tobacco addiction. Differing toxicity and pharmacological
N. P. Antonova, S. D. Kakhramanova, S. D. Alidzhanova, S. S. Prokhvatilova, E. P. Shefer   +4 more
doaj   +1 more source

St John’s wort (Hypericum perforatum) products – an assessment of their authenticity and quality [PDF]

, 2018
St John’s wort products (Hypericum perforatum L.) are widely available for sale in many countries including the UK via the internet. In the UK, these products are required to hold either a marketing authorisation or Traditional herbal registration (THR ...
Agapouda, A., Agapouda, A., Booker, A., Booker, A., Frommenwiler, D.A., Frommenwiler, D.A., Heinrich, P.M., Heinrich, P.M., Reich, E., Reich, E., Scotti, F., Scotti, F.   +11 more
core   +2 more sources

TABLETS. REGULATORY REQUIREMENTS OF THE STATE PHARMACOPOEIA XIII EDITION

Разработка и регистрация лекарственных средств, 2019
Comparative analysis of pharmacopoeial requirements for dosage forms tablets has been made due to the introduction of the State Pharmacopoeia of the Russian Federation XIII edition. An overview of changed requirements can be useful for revision (reissue)
N. V. Isaeva, A. I. Tulaykin, E. V. Sheshegova   +2 more
doaj  

Evaluation of the Possibility of Calculating LD50 and LD10 Using a Modified Script in the R Environment

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. The median lethal dose (LD50) and the low lethal dose (LD10) are critical parameters for the safety of medicinal products. Sometimes, the pharmacopoeial probit method (PM) fails to calculate the LD10 value, and the calculation result is ...
P. V. Shadrin
doaj   +1 more source

Pharmacognostical evaluation of aerial parts of Graptophyllum pictum (L.) Griff. (Syn: Justicia picta Linn.): A well-known folklore medicinal plant

Ancient Science of Life, 2015
Objective: Graptophyllum pictum (L.) Griff. (Family-Acanthaceae) occupies a key role in traditional system of medicine. Since an extensive literature survey did not provide any information about studies on its standardization.
Pradeep Singh, Ratan L Khosa, Garima Mishra, Keshri K Jha   +3 more
doaj   +1 more source

Substandard and counterfeit medicines: a systematic review of the literature [PDF]

, 2013
Objective: To explore the evidence available of poor quality (counterfeit and substandard) medicines in the literature. Design: Systematic review. Data sources: Databases used were EMBASE, MEDLINE, PubMed and the International Pharmaceutical Abstracts,
Almuzaini, Tariq, Choonara, Imti, Sammons, Helen   +2 more
core   +3 more sources

Pharmacognostical and Preliminary Phytochemical Studies of Argyreia nervosa Burm. [PDF]

, 2009
Pharmacognostical parameters for the leaves of Argyreia nervosa Burm were studied with the aim of drawing the pharmacopoeial standards for this species.
Krishnaveni, A., Thaakur, Santh Rani
core   +1 more source

Coherent anti-Stokes Raman Scattering (CARS) Microscopy Visualizes Pharmaceutical Tablets During Dissolution [PDF]

, 2014
Traditional pharmaceutical dissolution tests determine the amount of drug dissolved over time by measuring drug content in the dissolution medium. This method provides little direct information about what is happening on the surface of the dissolving ...
Fussell, A.L., Herek, J.L., Kleinebudde, P., Offerhaus, H.L., Strachan, C.J.   +4 more
core   +3 more sources