Results 41 to 50 of about 1,329 (193)

Small-scale dissolution test screening tool to select potentially substandard and falsified (SF) medicines requiring full pharmacopoeial analysis

Scientific Reports, 2021
The purpose of this study was to design a convenient, small-scale dissolution test for extracting potential substandard and falsified (SF) medicines that require full pharmacopoeial analysis. The probability of metronidazole samples complying with the US
Mohammad Sofiqur Rahman, Naoko Yoshida, Hirohito Tsuboi, Yuichiro Ishii, Yoshio Akimoto, Kazuko Kimura   +5 more
doaj   +1 more source

Standardisation of human immunoglobulin preparations: Harmonising Russian State pharmacopoeia with world quality standards

Биопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Human immunoglobulin preparations (HIP) used in medicine effectively treat autoimmune diseases, inflammatory diseases, and immune deficiencies and prevent diseases of various aetiologies.
O. A. Demidova, O. G. Kornilova, V. L. Bagirova   +2 more
doaj   +1 more source

Current aspects of Quality Control and Standardization of Eleutherococcus senticosus Medicines

Разработка и регистрация лекарственных средств, 2022
Introduction. Nowadays, herbal medicines are becoming more and more popular. In this regard, herbal medicinal preparations based on rhizomes and roots of Eleutherococcus senticosus (Rupr. & Maxim.) Maxim., syn. Acanthopanax senticosus (Rupr.
V. A. Kurkin, T. K. Ryazanova
doaj   +1 more source

Influence of Tropical Climate Conditions on the Quality of Antihypertensive Drugs from Rwandan Pharmacies [PDF]

, 2009
The objective of this study was to assess the quality of antihypertensive drugs and to investigate the influence of tropical storage conditions. Drug content and in vitro dissolution tests were performed on 10 test formulations (from Rwanda) and 6 ...
Cosijns, An, Pringels, Eveline, Remon, Jean Paul, Twagirumukiza, Marc, Van Bortel, Lucas, Vervaet, Chris   +5 more
core   +2 more sources

Certification of a pharmacopoeial reference standard for potency testing of adsorbed tetanus toxoid in guinea pigs

Биопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Currently, the national pharmacopoeial reference standard (RS) FSO.3.2.00247 for the potency of adsorbed tetanus toxoid (TT) is certified only in mice, whereas the WHO International Standard (IS) for TT is certified in two animal species ...
E. I. Komarovskaya, O. V. Fadeikina, K. A. Lysko, R. A. Volkova, O. G. Kornilova   +4 more
doaj   +1 more source

Enhancement of Manufacturing Technology for Finished Dosage Form of Bivalent Chemical Tableted Cholera Vaccine

Проблемы особо опасных инфекций, 2016
Objective of the study is to experimentally substantiate the possibility to improve manufacturing efficiency by means of mass reduction of a vaccine tablet from 300 to 100 mg. Materials and methods.
A. V. Komissarov, A. Yu. Ul’Yanov, O. A. Volokh, I. V. Shul’Gina, O. A. Lobovikova, O. D. Klokova, A. K. Nikiforov   +6 more
doaj   +1 more source

Advancements and future prospective of DNA barcodes in the herbal drug industry

Frontiers in Pharmacology, 2022
Ethnopharmacological relevance: The past couple of decades have witnessed the global resurgence of medicinal plants in the field of herbal-based health care.
Karthikeyan Mahima, Karthikeyan Mahima, Koppala Narayana Sunil Kumar, Kanakarajan Vijayakumari Rakhesh, Parameswaran Sathiya Rajeswaran, Ashutosh Sharma, Ramalingam Sathishkumar   +6 more
doaj   +1 more source

Determination of the optimal extractant for the extraction of biologically active substances of Sophora Flower–buds [PDF]

, 2020
Introduction.  According to the market products based on Sophora japonica L., extraction of biologically active substances, flavonoids in particular, is carried out with ethanol in a concentration 50–70%. However, in recent years, in literature data have
Bezruk, I, Konovalenko, I., Kriukova, A.
core   +2 more sources

Pharmacopoeias’ and manufacturers’ requirements for the quality of hard gelatin capsule shells

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. The lack of national requirements regulating the quality of empty hard gelatin capsule shells (before filling with medicines) causes difficulties not only for capsule developers and manufacturers but also for experts evaluating regulatory ...
E. L. Kovaleva, O. A. Matveeva, V. V. Shelestova, K. A. Balatskaya   +3 more
doaj   +1 more source

xperimental Evaluation of the Possibility of using the LAL test to Determine Bacterial Endotoxins in Vaccines for Rabies Prophylaxis

Эпидемиология и вакцинопрофилактика, 2021
Relevance. The presence of pyrogenic impurities in finished dosage forms of concentrated cultural anti-rabies vaccines produced in the Russian Federation is determined using pyrogenicity tests on rabbits (in vivo).
A. V. Muhacheva, O. A. Barkhaleva, O. V. Shapovalova, N. P. Neugodova, A. Yu. Butirskiy, A. A. Movsesyants, R. A. Volkova, K. A. Sarkisyan   +7 more
doaj   +1 more source