Results 61 to 70 of about 1,329 (193)

A Robust Static Headspace GC‐FID Method to Detect and Quantify Formaldehyde Impurity in Pharmaceutical Excipients

Journal of Analytical Methods in Chemistry, Volume 2018, Issue 1, 2018., 2018
Formaldehyde is a highly reactive impurity that can be found in many pharmaceutical excipients. Trace levels of this impurity may affect drug product stability, safety, efficacy, and performance. A static headspace gas chromatographic method was developed and validated to determine formaldehyde in pharmaceutical excipients after an effective ...
Bashir Daoud Agha Dit Daoudy, Mohammad Ammar Al-Khayat, Francois Karabet, Mohammad Amer Al-Mardini, Krishna K. Verma   +4 more
wiley   +1 more source

Problems of Assessment of Live Bacterial Vaccine Sterility

Проблемы особо опасных инфекций, 2019
Objective of the study - analysis of standard indicators and methods, utilized for determination of presence of contaminating microorganisms in live bacterial vaccines. Materials and methods.
S. M. Sukhanova, L. V. Sayapina, Z. E. Berdnikova, A. S. Tikhonova, V. I. Klimov   +4 more
doaj   +1 more source

Topical and transdermal botanical formulations of the Chinese pharmacopoeia—A review

Phytotherapy Research, Volume 38, Issue 9, Page 4716-4735, September 2024.
Abstract In pharmaceutics, ingredients are classified as active ingredients and excipients. In topical/transdermal phytomedicines, an ingredient may serve both functions. Published information on these dual‐purpose ingredients and their pharmacological relevance is limited.
Jingyi Gu, Majella E. Lane, Bruno Da Silva Sil Dos Santos, Michael Heinrich   +3 more
wiley   +1 more source

Safety of hydroxyanthracene derivatives for use in food

EFSA Journal, Volume 16, Issue 1, January 2018., 2018
Abstract The Panel on Food Additives and Nutrient Sources added to Food (ANS) was asked to deliver a scientific opinion on the safety of hydroxyanthracene derivatives and to provide advice on a daily intake that does not give rise to concerns about harmful effects to health.
EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), Maged Younes, Peter Aggett, Fernando Aguilar, Riccardo Crebelli, Metka Filipič, Maria Jose Frutos, Pierre Galtier, David Gott, Ursula Gundert‐Remy, Gunter Georg Kuhnle, Claude Lambré, Jean‐Charles Leblanc, Inger Therese Lillegaard, Peter Moldeus, Alicja Mortensen, Agneta Oskarsson, Ivan Stankovic, Ine Waalkens‐Berendsen, Rudolf Antonius Woutersen, Raul J Andrade, Cristina Fortes, Pasquale Mosesso, Patrizia Restani, Fabiola Pizzo, Camilla Smeraldi, Adamantia Papaioannou, Matthew Wright   +27 more
wiley   +1 more source

Mass uniformity of compounded powders divided into gelatin capsules [PDF]

Farmacja Polska, 2020
Background Capsules are one of the most popular oral dosage forms compounded in a pharmacy. They are filled with pulverized active substance, often mixed with glucose or lactose as a diluting agent and filler.
Monika Gajewska, Małgorzata Sznitowska, Marcin Płaczek   +2 more
doaj   +1 more source

Extraction solvent selection for Cannabis sativa L. by efficient exploration of cannabinoid selectivity and phytochemical diversity

Phytochemical Analysis, Volume 35, Issue 1, Page 163-183, January 2024.
Abstract Introduction Cannabis sativa L. is attracting worldwide attention due to various health‐promoting effects. Extraction solvent type is critical for the recovery of bioactive compounds from the plant, especially cannabinoids. However, the choice of solvent is varied and not adequately warranted elsewhere, causing confusion in involved fields ...
Petros S. Tzimas, Eleftherios A. Petrakis, Maria Halabalaki, Leandros A. Skaltsounis   +3 more
wiley   +1 more source

Development of HPLC method for identification and quantification of genistein substance

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. low-toxic polyphenolic compound with significant antioxidant activity. Genistein Genistein (5,7-dihydroxy-3-(4-hydroxyphenyl)chromene-4-on) is in combination with chemoradiotherapy can prevent and reduce radiation damage.
L. D. Ignatova, V. V. Tihonova, O. Yu. Strelova   +2 more
doaj   +1 more source

MICROSCOPIC DIAGNOSTIC FEATURES OF WHOLE, MILLED AND POWDERED PLANT MATERIAL “RHIZOMES OF COMMON TURMERIC”

Наука и инновации в медицине, 2016
Aim - the determination of microscopic diagnostic features of rhizomes of common turmeric (Curcuma longa L.), ginger family (Zingiberaceae). Materials and methods.
VA A Kurkin, VM M Ryzhov, TK K Ryazanova, LV V Tarasenko, MYu Yu Borisov, EV V Avdeeva   +5 more
doaj   +1 more source

Fast disintegrating crystalline solid dispersions of simvastatin for incorporation into orodispersible tablets [PDF]

, 2014
Aim : Spray dried solid dispersion (SDP) of crystalline simvastatin (SIM) in a fast disintegrating matrix of superdisintegrants was studied as a method to enhance SIM dispersibility, rheology, compactibility and compressibility for incorporation into ...
Ambike, Broadhead, Chowdary, De, Doelker, Frizon, Fu, Goddeeris, Gonnissen, Joiris, Jun, Kang, Margulis-Goshen, Moneghini, Mukharya, Pabari, Pabari, Patel, Puttipipatkhachorn, Ramtoola, Rytting, Sareen, Sharma, Shi, Simões, Whiteman, Yang, Yen, Yoshinari, Yu, Zimper   +30 more
core   +2 more sources

THE STUDY OF THE EXTRACTION DYNAMICS OF BIOLOGICALLY ACTIVE SUBSTANCES FROM THE BIDENS TRIPARTITA L. HERB AND ANTIOXIDANT ACTIVITY OF THE OBTAINED EXTRACTS [PDF]

, 2020
The interest to study the genus Bidens and in particular Bidens tripartita L. (bur-marigold herb) is unmitigated due to its antioxidant, anti-allergic, antimicrobial, antifungal, hepatoprotective, immunostimulating and hypotensive activity ...
Bezruk, Ivan, Gontova, Tetiana, Kotov, Andrii, Kotov, Semen, Kotova, Elina   +4 more
core   +3 more sources