Results 41 to 50 of about 3,108 (188)

Assessment and Control of Organic Impurities in Medicinal Products: A Review

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. The determination of impurities is a key requirement for the quality assessment of medicines because impurities can significantly impact the quality and therapeutic effectiveness.
O. A. Matveeva, E. L. Kovaleva, A. A. Ponomarenko   +2 more
doaj   +1 more source

Re-framing ‘counterfeit from a public health perspective’: A case for fraudulent medicine [PDF]

, 2016
Author version made available in accordance with publisher copyright policy.“Black market” counterfeiters operating outside of authorised industry are often framed as the perpetrators of dangerous and defective medicines within legal pharmaceutical ...
Bandiera, Rhiannon, Marmo, Marinella
core   +1 more source

Rethinking the AI Paradigm for Solubility Prediction of Drug‑Like Compounds with Dual‐Perspective Modeling and Experimental Validation

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Aqueous solubility governs drug delivery and bioavailability, yet its prediction remains challenging. Utilizing the largest curated dataset of drug‐like molecules, prediction models are constructed through dual‐perspective benchmarking. Stacking methods outperform advanced deep learning due to data constraints. These validated models enabled systematic
Qilin Zhu, Yuxin Qiu, Guzhong Chen, Wenyao Chen, Xiang Zhang, Zhiwen Qi, Xuezhi Duan, De Chen, Zhen Song   +8 more
wiley   +1 more source

Certification of a pharmacopoeial reference standard for potency testing of recombinant interferon α-2b

Биопрепараты: Профилактика, диагностика, лечение
SCIENTIFIC RELEVANCE. Potency testing of recombinant interferons requires a reference standard. The availability of International Standards (ISs) that are commonly used to assess the quality of recombinant interferons is currently limited. Therefore, the
L. A. Gaiderova, Yu. N. Lebedeva, T. N. Lobanova, E. K. Lipatova, R. A. Volkova, O. V. Fadeikina   +5 more
doaj   +1 more source

Determination of Anthracene Derivatives in Herbal Medicines

Регуляторные исследования и экспертиза лекарственных средств, 2021
The relevance of this study stems from the need for alignment of test methods used for identification and assay of anthracene derivatives in herbal preparations and herbal medicinal products.
O. V. Evdokimova, A. V. Beketova, M. N. Lyakina   +2 more
doaj   +1 more source

A Novel Semi‐Automated Pipeline for Optimizing 3D‐Printed Drug Formulations

Advanced Intelligent Systems, Volume 7, Issue 11, November 2025.
A novel, semi‐automated deep learning and differential evolution pipeline designed for generating medicines for 3D‐printed medicines is introduced. This pipeline successfully generates a diverse range of drug formulations with an 80% printing success rate and 92% accuracy in predicting printing parameters.
Youssef Abdalla, Martin Ferianc, Haya Alfassam, Atheer Awad, Ruochen Qiao, Miguel Rodrigues, Mine Orlu, Abdul W. Basit, David Shorthouse   +8 more
wiley   +1 more source

Challenges relating to comparison of flavonoid glycosides dissolution profiles from Sutherlandia frutescens products [PDF]

, 2017
Unlike the case of conventional drug formulations, dissolution tests have hitherto not been required for herbal medicinal products commercially available in South Africa.
Cordes, David B., Delforce, Lucie, Jacquemin, Denis, Rota Martir, Diego, Slawin, Alexandra M. Z., Warriner, Stuart, Zysman-Colman, Eli   +6 more
core   +6 more sources

In vitro evaluation of marketed antimalarial chloroquine phosphate tablets [PDF]

, 2005
Background & objectives: The aim of the present study is to investigate the physicochemicalequivalence of seven brands of tablets containing chloroquine phosphate, an antimalarial purchasedfrom different retail pharmacy outlets.Methods: The quality and ...
Amit K. Patel, Bhupendra G. Prajapati, Rubina S. Moria & Chhaganbhai N. Patel
core  

Potential of a cyclone prototype spacer to improve in vitro dry powder delivery [PDF]

, 2013
Copyright The Author(s) 2013. This article is published with open access at Springerlink.com. This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium ...
A Nair, A Voss, AJ Hickey, AR Clark, C Terzano, CG Thiel, D Ganderton, Darragh Murnane, DI Daniher, Digby D. Symons, EA Matida, F Lavorini, F Lavorini, H Bisgaard, H Bisgaard, H Bisgaard, H Chrystyn, Irene Parisini, JP Mitchell, K Demirkan, K Svartengren, L Borgstrom, L Borgström, LI Harrison, M Hindle, MEAC Broeders, ML Everard, N Islam, P Begat, PW Barry, R Buhl, R Pauwels, RAM Al-Showair, Sean J. Cheng, SP Newman, T Ehtezazi, T Srichana, T Srichana, WES Kamin, WH DeHaan, WY Tarsin, XM Zeng   +41 more
core   +2 more sources

Model‐informed exploration of the boundaries of safe aluminium exposure from allergen immunotherapy in children

Pediatric Allergy and Immunology, Volume 36, Issue 8, August 2025.
Abstract Background The safety of aluminium (Al) exposure from medicinal products for subcutaneous allergen immunotherapy (SCIT) is still under debate due to their administration in many doses over years. Especially for children, model‐informed risk assessment is urgently needed in the absence of clinical study data.
Karin Weisser, Gaby Wangorsch, Niklas Hartung, Wilhelm Huisinga, Brigitte Keller‐Stanislawski   +4 more
wiley   +1 more source