Results 41 to 50 of about 3,147 (187)

In vitro evaluation of marketed antimalarial chloroquine phosphate tablets [PDF]

, 2005
Background & objectives: The aim of the present study is to investigate the physicochemicalequivalence of seven brands of tablets containing chloroquine phosphate, an antimalarial purchasedfrom different retail pharmacy outlets.Methods: The quality and ...
Amit K. Patel, Bhupendra G. Prajapati, Rubina S. Moria & Chhaganbhai N. Patel
core  

Rethinking the AI Paradigm for Solubility Prediction of Drug‑Like Compounds with Dual‐Perspective Modeling and Experimental Validation

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Aqueous solubility governs drug delivery and bioavailability, yet its prediction remains challenging. Utilizing the largest curated dataset of drug‐like molecules, prediction models are constructed through dual‐perspective benchmarking. Stacking methods outperform advanced deep learning due to data constraints. These validated models enabled systematic
Qilin Zhu, Yuxin Qiu, Guzhong Chen, Wenyao Chen, Xiang Zhang, Zhiwen Qi, Xuezhi Duan, De Chen, Zhen Song   +8 more
wiley   +1 more source

Certification of a pharmacopoeial reference standard for potency testing of recombinant interferon α-2b

Биопрепараты: Профилактика, диагностика, лечение
SCIENTIFIC RELEVANCE. Potency testing of recombinant interferons requires a reference standard. The availability of International Standards (ISs) that are commonly used to assess the quality of recombinant interferons is currently limited. Therefore, the
L. A. Gaiderova, Yu. N. Lebedeva, T. N. Lobanova, E. K. Lipatova, R. A. Volkova, O. V. Fadeikina   +5 more
doaj   +1 more source

A Novel Semi‐Automated Pipeline for Optimizing 3D‐Printed Drug Formulations

Advanced Intelligent Systems, Volume 7, Issue 11, November 2025.
A novel, semi‐automated deep learning and differential evolution pipeline designed for generating medicines for 3D‐printed medicines is introduced. This pipeline successfully generates a diverse range of drug formulations with an 80% printing success rate and 92% accuracy in predicting printing parameters.
Youssef Abdalla, Martin Ferianc, Haya Alfassam, Atheer Awad, Ruochen Qiao, Miguel Rodrigues, Mine Orlu, Abdul W. Basit, David Shorthouse   +8 more
wiley   +1 more source

Determination of Anthracene Derivatives in Herbal Medicines

Регуляторные исследования и экспертиза лекарственных средств, 2021
The relevance of this study stems from the need for alignment of test methods used for identification and assay of anthracene derivatives in herbal preparations and herbal medicinal products.
O. V. Evdokimova, A. V. Beketova, M. N. Lyakina   +2 more
doaj   +1 more source

Analytical Method by Headspace‐Gas Chromatography for Determination of Six Residual Solvents in Losartan Potassium Raw Material

Journal of Separation Science, Volume 48, Issue 11, November 2025.
ABSTRACT Residual solvents, or organic volatile impurities, are a potential toxic risk for pharmaceutical products and have been a manufacturers’ concern for many years. Moreover, residual solvents can also affect the quality and stability of not only drug substances but also of drug products.
Vanessa B. de Camargo, Cássia V. Garcia
wiley   +1 more source

Mebendazole spectrophotometric determination: theorical and experimental study of the interaction with sodium hydroxide [PDF]

, 2016
USP, EP, and Argentinian Pharmacopoeia proposed HPLC-UV for quantitative quality control of mebendazole (MBZ) tablets. In this work, a spectrophotometric method is proposed.
Delfino, Mario Raul, Jorge, Nelly Lidia, Monzón, Celina María, Sarno, María del Carmen Teresa   +3 more
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Multifunctional nanocarriers for lung drug delivery [PDF]

, 2020
Nanocarriers have been increasingly proposed for lung drug delivery applications. The strategy of combining the intrinsic and more general advantages of the nanostructures with specificities that improve the therapeutic outcomes of particular clinical ...
Grenha, Ana, Pontes, Jorge Filipe
core   +2 more sources

Model‐informed exploration of the boundaries of safe aluminium exposure from allergen immunotherapy in children

Pediatric Allergy and Immunology, Volume 36, Issue 8, August 2025.
Abstract Background The safety of aluminium (Al) exposure from medicinal products for subcutaneous allergen immunotherapy (SCIT) is still under debate due to their administration in many doses over years. Especially for children, model‐informed risk assessment is urgently needed in the absence of clinical study data.
Karin Weisser, Gaby Wangorsch, Niklas Hartung, Wilhelm Huisinga, Brigitte Keller‐Stanislawski   +4 more
wiley   +1 more source

TABLETS. REGULATORY REQUIREMENTS OF THE STATE PHARMACOPOEIA XIII EDITION

Разработка и регистрация лекарственных средств, 2019
Comparative analysis of pharmacopoeial requirements for dosage forms tablets has been made due to the introduction of the State Pharmacopoeia of the Russian Federation XIII edition. An overview of changed requirements can be useful for revision (reissue)
N. V. Isaeva, A. I. Tulaykin, E. V. Sheshegova   +2 more
doaj