Results 71 to 80 of about 3,108 (188)

Standardisation of the method of residual organic solvent determination (review)

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. An important quality attribute of medicines and excipients is the content of residual organic solvents (ROS). The general chapter on ROS (1.1.0008) of the State Pharmacopoeia of the Russian Federation (Ph.
O. G. Kornilova, E. A. Smiryagin, V. L. Bagirova, M. A. Sumtsov   +3 more
doaj   +1 more source

Comparative Evaluation of Assay Methods Used to Determine Anthracene Derivatives in Herbal Substances and Herbal Medicinal Products

Регуляторные исследования и экспертиза лекарственных средств, 2018
The use of assay methods with different test conditions for determination of anthracene derivatives in herbal substances and herbal medicinal products requires adjustment of the established limits for total anthracene derivatives content based on the ...
N. P. Antonova, I. M. Morgunov, S. S. Prokhvatilova, E. P. Shefer, A. M. Kalinin   +4 more
doaj   +1 more source

Topical and transdermal botanical formulations of the Chinese pharmacopoeia—A review

Phytotherapy Research, Volume 38, Issue 9, Page 4716-4735, September 2024.
Abstract In pharmaceutics, ingredients are classified as active ingredients and excipients. In topical/transdermal phytomedicines, an ingredient may serve both functions. Published information on these dual‐purpose ingredients and their pharmacological relevance is limited.
Jingyi Gu, Majella E. Lane, Bruno Da Silva Sil Dos Santos, Michael Heinrich   +3 more
wiley   +1 more source

Modern approaches to drafting general and individual monographs on human blood products

Регуляторные исследования и экспертиза лекарственных средств, 2018
Blood products were first represented in the State Pharmacopoeia of the USSR IX and X editions (1961 and 1968) by a single monograph "Gamma globulin for the prevention of measles".
A. V. Karyakin, T. M. Kargina, E. I. Sakanyan, I. G. Osipova, A. A. Movsesyants, E. Y. Kudasheva   +5 more
doaj  

Unblocking high-value botanical value chains: Is there a role for blockchain systems? [PDF]

, 2019
Blockchain systems are a fast emerging and a currently widely discussed novel strategy for a decentralised cryptographically-enhanced digital ledger recording transactions among stakeholders.
Booker, A., Booker, A., Fitzgerald, M., Fitzgerald, M., Heinrich, M., Heinrich, M., Kum, K.Y., Kum, K.Y., Lobel, K., Lobel, K., Scotti, F., Scotti, F.   +11 more
core   +3 more sources

Functions of Epimedin C in a zebrafish model of glucocorticoid‐induced osteoporosis

Journal of Cellular and Molecular Medicine, Volume 28, Issue 14, July 2024.
Abstract Epimedium is thought to enhance the integrity of tendons and bones, ease joint discomfort and rigidity and enhance kidney function. Although glucocorticoids are commonly used in clinical practice, the mechanism by which the active compound Epimedin C (EC) alleviates glucocorticoid‐induced osteoporosis (GIOP) is not well understood.
Xiaoyang Zhou, Kai Lian, Junjie Jia, Xue Zhao, Peng Duan, Jiaolong Huang, Yihua Shi   +6 more
wiley   +1 more source

Methodological Approaches to Determination of Depressor Substances in Medicinal Products

Регуляторные исследования и экспертиза лекарственных средств, 2020
In order to harmonise national and foreign requirements for quality control of medicinal products, a second variant of the test method, which complies with the requirements of the European Pharmacopoeia, was included into the general monograph OFS.1.2.4 ...
T. A. Batuashvili, L. V. Simutenko, N. P. Neugodova, P. V. Shadrin   +3 more
doaj   +1 more source

A Simple and Sensitive HPTLC Method for Simultaneous Determination of Metformin Hydrochloride and Sitagliptin Phosphate in Tablet Dosage Form [PDF]

, 2013
A simple, rapid, and precise high-performance thin-layer chromatographic (HPTLC) method for simultaneous estimation of two antidiabetic drugs, metformin hydrochloride and sitagliptin phosphate, in tablet dosage form has been developed and validated ...
Bhavesh H. Patel, Darshana K. Modi, Punit B. Parejiya   +2 more
core   +1 more source

Accelerated and intensified manufacturing of an adenovirus‐vectored vaccine to enable rapid outbreak response

Biotechnology and Bioengineering, Volume 121, Issue 1, Page 176-191, January 2024.
Abstract The Coalition for Epidemic Preparedness Innovations' “100‐day moonshot” aspires to launch a new vaccine within 100 days of pathogen identification, followed by large‐scale vaccine availability within the “second hundred days.” Here, we describe work to optimize adenoviral vector manufacturing for rapid response, by minimizing time to clinical ...
Carina C. D. Joe, Rameswara R. Segireddy, Cathy Oliveira, Adam Berg, Yuanyuan Li, Dimitrios Doultsinos, Steffi Scholze, Asma Ahmad, Piergiuseppe Nestola, Julia Niemann, Alexander D. Douglas   +10 more
wiley   +1 more source

Water for injections: Global trends in pharmacopoeial quality assessment and Russian expert practice

Биопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. High quality standards for sterilised water for injections arise from the need to guarantee the safety and effectiveness of injectable medicines, especially biologicals, since the presence of impurities in the solvent (mainly microbial ...
S. M. Sukhanova, A. A. Semenov, N. M. Minaeva   +2 more
doaj   +1 more source