Results 41 to 50 of about 4,953 (183)

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko   +9 more
wiley   +1 more source

Medical versus science students: Knowledge, perceptions and learning of core pharmacology concepts

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Pharmacology is a core discipline underpinning both medical and biomedical science education, essential for understanding drug action, safety and therapeutic efficacy. This study compared pharmacology knowledge, perceptions and learning experiences between second‐year medical and science students to evaluate how effectively each curriculum ...
Zina Alfahl   +3 more
wiley   +1 more source

Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy   +3 more
wiley   +1 more source

Avaliação da adesão e qualidade de vida de portadores de HIV sob seguimento farmacoterapêutico / Evaluation of adhesion and quality of life of HIV carriers under pharmacoterapeutical follow up

open access: yesRevista Ciências em Saúde, 2017
Introdução: O seguimento farmacoterapêutico (STF) de pacientes com HIV tem grande importância, pois contribui para adesão ao tratamento. Objetivos: Avaliar adesão e qualidade de vida em pacientes em uso de terapia antirretroviral através de questionários
Larissa Rocha Arruda de Souza   +5 more
doaj   +1 more source

Spanish Society of Hospital Pharmacy Position Statement on Telepharmacy: Recommendations for its implementation and development [PDF]

open access: yesFarmacia Hospitalaria, 2020
The use of information and communication technologies have nowadays become part and parcel of hospital pharmacy practice. Against this background, it is hardly surprising that Telepharmacy has sparked the interest of a large number of stakeholders. In
Ramón Morillo-Verdugo   +7 more
doaj   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi   +6 more
wiley   +1 more source

A review of the pathophysiology and the role of ion channels on bronchial asthma

open access: yesFrontiers in Pharmacology, 2023
Asthma is one of the main non-communicable chronic diseases and affects a huge portion of the population. It is a multifactorial disease, classified into several phenotypes, being the allergic the most frequent. The pathophysiological mechanism of asthma
Indyra Alencar Duarte Figueiredo   +8 more
doaj   +1 more source

White Matter Dysfunction and Neurotransmitter Basis Underlying the Freezing of Gait in Parkinson's Disease

open access: yesiNew Medicine, EarlyView.
In the freezing of gait in Parkinson's disease, white matter shows decreased local activity but increased functional connectivity. These distinct dysfunctions are uniquely associated with specific neurotransmitter systems (GABA, dopamine, etc.), mapping a new neurochemical basis for this debilitating symptom. ABSTRACT Freezing of gait (FOG) is a severe
Pingping Liu   +10 more
wiley   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

open access: yesiNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu   +5 more
wiley   +1 more source

Predictive factors of hyperglycemia in hospitalized adults receiving total parenteral nutrition [PDF]

open access: yesFarmacia Hospitalaria, 2017
Objective: To know those predictive factors of hyperglycemia that could guide us the design of a parenteral nutrition and it could avoid later complications associated with it. Methods: A prospective observational study was designed; adult hospitalized
Teresa García Martínez   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy