Results 161 to 170 of about 51,036 (300)

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Pharmacokinetic and Pharmacodynamic Interactions Between Anti‐Asthma Drugs and Medicinal Plants: A Comprehensive Review

Phytotherapy Research, EarlyView.
ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit, Aylin Bülbül, Betul Kocaadam‐Bozkurt, Osman Bozkurt, Duygu Ağagündüz, Raffaele Capasso   +5 more
wiley   +1 more source

Multi‐Target Pharmacological Mechanisms of Salvia miltiorrhiza Bunge in Metabolic Syndrome and Cardiovascular Diseases: A Comprehensive Review Based on the Theory of “Same Treatment for Different Diseases”

Phytotherapy Research, EarlyView.
Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia, Kaiyi Wu, Jiaying Qi, Nana Huang, Yusheng Liu, Xiumei Gao, Rong Sun   +6 more
wiley   +1 more source

Artificial intelligence and computational methods in the Asia-Pacific pharmacovigilance landscape: a systematic review. [PDF]

Int J Public Health
Kusnadi G, Wangge G, Perdana A.
europepmc   +1 more source

Treatment Patterns and Pathways of Systemic Drug Therapy in Patients With Plaque, Erythrodermic, and Generalized Pustular Psoriasis: A Retrospective Cohort Study in Japan

The Journal of Dermatology, EarlyView.
ABSTRACT Systemic psoriasis treatment options have rapidly expanded in Japan, including the approval of tyrosine kinase 2 and interleukin‐36 receptor inhibitors in 2022. However, contemporary real‐world treatment patterns across plaque, erythrodermic, and generalized pustular psoriasis remain incompletely characterized.
Yayoi Tada, Yoshiko Maeda, Miyuki Hasegawa, Motonobu Sakaguchi, Takamasa Hashimoto, Teruko Narusawa, Nobuyoshi Takabayashi, Tomoko Takahashi, Taisuke Kondo, Shingo Kuroda   +9 more
wiley   +1 more source

Tubulointerstitial Nephritis Induced by Adalimumab

Turkish Journal of Nephrology
Yasmine Salem Mahjoubi , Widd Kaabi , Ghozlane Lakhoua , Ahmed Zaiem, Riadh Daghfous , Imen Aouinti, Sihem El Aidli   +6 more
doaj   +1 more source

Governing AI for Pharmacovigilance in Low-Income Countries: Systems Perspective. [PDF]

J Med Internet Res
Dut GM.
europepmc   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Pregnancy: Periconception Exposure and Perinatal Outcomes

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective An increasing number of women of childbearing age worldwide are using glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and are advised to use effective contraception during treatment. Nevertheless, maternity services are encountering increasing numbers of women exposed to GLP‐1 RAs shortly before conception or during pregnancy ...
Katherine G. Y. Lau, Anisha Chopra, Edward Mullins, Rochan Agha‐Jaffar, Tricia Tan, Lynne Sykes, Christina K. H. Yu   +6 more
wiley   +1 more source

Burden and Risk of Depression in Patients Receiving Semaglutide: A Systematic Review and Meta-Analysis. [PDF]

Clin Obes
Bhaduri G, Roy S, Kalia A, Gokalani R, Saboo B.   +4 more
europepmc   +1 more source

Evaluating the impact of varenicline shortages and a regulatory mitigation strategy on dispensing patterns of smoking cessation therapies in Australia: A retrospective interrputed time series study

Addiction, EarlyView.
Abstract Background and aims Australia experienced a prolonged varenicline shortage beginning June 2021, disrupting access to a key smoking cessation therapy. Section 19A (S19A) of the Therapeutic Goods Act permitted temporary importation of overseas‐approved products to mitigate this impact.
Chloe Weigall, Lisa Kalisch Ellett, Anna Kemp‐Casey, Nicole Pratt, Jacinta L. Johnson, Stephanie E. Reuter, Jack Luke Janetzki   +6 more
wiley   +1 more source