Results 41 to 50 of about 48,983 (212)
Appraising the visibility, relevance and impacts of clinical pharmacology
Aims Clinical pharmacology (CP) used to be a strong medical and scientific field, but during the last three decades it seems to have lost some of its appeal. We reviewed the visibility, relevance and impact of CP and clinical pharmacologists across the globe and suggest ways to strengthen the discipline to address future pharmacotherapeutic challenges.
Serge Cremers+5 more
wiley +1 more source
Jordan Food and Drug Administration (JFDA) is an independent institution responsible for protecting the Jordanian public health through ensuring the safety, efficacy, and security of medicines and health technologies, as well as ensuring the safety of the food supply reaching consumers in Jordan.
openaire +2 more sources
Pharmacovigilance – The next chapter [PDF]
The discovery and quantification of adverse drug reactions has long relied on the careful analysis of spontaneously reported cases. Causality assessment (imputation) was a fundamental feature of individual case report analysis. This was complemented by analysis of aggregated cases, and of disproportionality analyses in spontaneous reports databases. In
Moore, Nicholas+3 more
openaire +3 more sources
New drug development is a challenging and costly process as it involves focus on quality, efficacy as well as safety. Some of the adverse drug reactions (ADRs) are predicted based upon the previous experience with the pharmacologically similar drugs and others are detected during clinical trials.
Niranjan Munjal+3 more
openaire +3 more sources
Aims The French government's IATROPREV program has been designed to assess the effectiveness and safety of medications prescribed to older adults discharged from acute geriatric units. IATROPREV includes the implementation of a personalized pharmaceutical plan validated at a multidisciplinary meeting attended by the patient's geriatrician, family ...
Chloé Cornille+13 more
wiley +1 more source
Aims Several methods exist to identify hospital admissions related to adverse drug events (ADEs). Clinical adjudication by healthcare professionals is the gold standard but is labour‐intensive. Spontaneous reporting and routinely collected healthcare data using a set of International Classification of Diseases (ICD) codes often underestimate the ...
Zuzana Juhásová+2 more
wiley +1 more source
X‐ray controlled release strategy in cancer therapy
A comprehensive review on the design principles and current strategies of X‐ray stimulated release systems in cancer therapy, focusing on the X‐ray responsive functional groups and materials as well as discussing the advantages and current challenges of X‐ray controlled release systems in cancer therapy.
Yiling Ruan+5 more
wiley +1 more source
Objective: Cancer remains a global health challenge, necessitating new therapeutic options. Phytochemicals, with diverse chemical structures and biological activities, show promise as anticancer agents. This review explores key phytochemicals, their mechanisms, and their potential integration into cancer therapy.
Alaa A. A. Aljabali+11 more
wiley +1 more source
Clinical trials on medicinal products in Malta following EU accession [PDF]
Following EU Accession, Malta has to adopt EU Directives as part of its own legislation. Three such directives concern the conduct of clinical trials in European countries 2001/20/EC, 2003/94/EC and 2005/28/EC.
Calleja, Neville, Ellul, Ian C.
core
Semi-Supervised Recurrent Neural Network for Adverse Drug Reaction Mention Extraction
Social media is an useful platform to share health-related information due to its vast reach. This makes it a good candidate for public-health monitoring tasks, specifically for pharmacovigilance.
Gupta, Shashank+4 more
core +1 more source