Results 201 to 210 of about 27,161 (265)

Reflex Syncope With Complete Heart Block Triggered by Swallowing in a Patient on Immune Checkpoint Inhibitor Therapy

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) are now standard of care for most advanced solid tumors. While effective, they are associated with immune‐related adverse events (irAEs), including rare autonomic complications. We present a patient with metastatic lung adenocarcinoma receiving nivolumab and ipilimumab who developed reflex syncope with ...
Ashley Bouzon, Michael Oropesa, Bardia Adibmoradi, Daniel Weitz   +3 more
wiley   +1 more source

Prevalence and risk factors of potentially inappropriate medications at discharge in older adults with heart failure: A retrospective observational pharmacovigilance study. [PDF]

Medicine (Baltimore)
Xu J, Zhang L, Ma H, Lu Y, Jiang Z.
europepmc   +1 more source

Safety and tolerance of oral ketamine: A systematic review

Psychiatry and Clinical Neurosciences, EarlyView.
Oral ketamine has gained increasing interest beyond anesthesia, particularly for treatment‐resistant depression, chronic pain, and pediatric procedural sedation. Despite expanding off‐label use, there is no standardized pharmaceutical formulation, and long‐term safety remains uncertain.
Nathalia Novaretti, Rebeca Mendes P. Pessoa, Jaime Eduardo Cecílio Hallak, Rafael Guimarães dos Santos, Marcos Hortes N. Chagas   +4 more
wiley   +1 more source

ADHD medications and drug withdrawal: A pharmacovigilance study using the FDA Adverse Event Reporting System (FAERS) database. [PDF]

PCN Rep
Ebina T, Iwamoto K, Ikeda M.
europepmc   +1 more source

Clinical performance and limitations of a vital sign‐based electronic automatic notification system for suspected transfusion reactions: A 6‐year experience

Transfusion, EarlyView.
Abstract Background Automated surveillance systems such as the electronic automatic notification system (EANS) have been introduced to improve recognition of adverse transfusion reactions (ATRs), but their long‐term sustainability and operational limitations remain incompletely defined. Study Design and Methods We conducted a 6‐year retrospective study
Young Ae Lim, Chorong Park, Jin Kim
wiley   +1 more source

Cutaneous adverse reactions associated with enfortumab vedotin: a pharmacovigilance study based on the FDA adverse event reporting system. [PDF]

Front Med (Lausanne)
Ding P, Luo Q, Cao L.
europepmc   +1 more source

Comparative Risks of Pregnancy Complications in Women Prescribed Psychostimulants or Atomoxetine During Pregnancy Following Pre‐Pregnancy Stimulant Use

Psychiatric Research and Clinical Practice, EarlyView.
Objective Prescription stimulants are commonly used to manage attention deficit hyperactivity disorder among women of reproductive age, yet their safety during pregnancy remains unclear. This study leveraged large‐scale electronic health record data to assess whether use of these medications during pregnancy was associated with adverse pregnancy ...
Wen‐Jan Tuan, Nandini Sarkar, Paul Griffin, Dara E. Babinski   +3 more
wiley   +1 more source

Post-market safety profile and suicide risk signals of vortioxetine: a real-world pharmacovigilance study. [PDF]

Front Pharmacol
Qiu G, Ye D, Xu X.
europepmc   +1 more source

The “GABAergic Brake” on the Spinal Defecation Reflex: A Proposed Neurobiological Model Explaining Clozapine‐ and Benzodiazepine‐Induced Gastrointestinal Hypomotility and Ogilvie's Syndrome

Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
Synergistic “Double Brake” Model on the Spinal Defecation Center in Clozapine‐Induced Constipation. Real‐world data shows BZDRs increase laxative risk in schizophrenia. Mitigating the central GABAergic brake via sedative optimization and maintaining gut microbiota homeostasis prevents fatal Ogilvie's syndrome.
Takahiko Nagamine
wiley   +1 more source

Real-world safety profile of mosunetuzumab: a pharmacovigilance study based on the food and drug administration adverse event reporting system. [PDF]

Front Pharmacol
Liu J, Zhang Y, Yang T, Zhang L, Luo Y, Zhang J, Zhang R.   +6 more
europepmc   +1 more source