Results 71 to 80 of about 27,161 (265)

What Affects the Quality of Pharmacovigilance? Insights From Qualitative Comparative Analysis

Pharmacology Research & Perspectives
Pharmacovigilance plays a significant role in guaranteeing the safety of medications for patients. Over the last three decades, China has significantly advanced its pharmacovigilance practices, yet the factors that drive the quality of pharmacovigilance ...
Yadong Wang, Yue Chen, Xingjuan Xu, Ting Ying, Runan Xia, Yuanyuan Zhang, Xuefeng Xie   +6 more
doaj   +1 more source

Assessment of pharmacovigilance knowledge and ADR reporting skills in undergraduate medical students using the OSPA model

Dialogues in Health
Background: Pharmacovigilance (PV) and adverse drug reaction (ADR) reporting are essential components of ensuring medication safety. However, many healthcare students have limited knowledge in these areas.
T.Y. Sree Sudha, Kusum Kumari, C. Vasantha Kalyani, Monika Kankarwal, K.S.B.S. Krishna Sasanka   +4 more
doaj   +1 more source

A questionnaire based study to assess knowledge, attitude and practice of pharmacovigilance among undergraduate medical students in a Tertiary Care Teaching Hospital of South India

Perspectives in Clinical Research, 2015
Objectives: Spontaneous reporting of adverse drug reaction (ADR) is the backbone of pharmacovigilance program. Under reporting by prescribers is still exist.
Bikash Ranjan Meher, N Joshua, B Asha, Deepali Mukherji   +3 more
doaj   +1 more source

Do consumers and healthcare professionals report the same adverse event differently? A paired analysis of duplicate vaccine safety reports in Norway

British Journal of Clinical Pharmacology, EarlyView.
Aim This study aimed to compare how Norwegian healthcare professionals (HCPs) and consumers reported the same adverse event (AE) following immunization with vaccines against COVID‐19 during the COVID‐19 pandemic. Specifically, we aimed to compare the extent to which HCPs and consumers reported information relevant for assessing the causal relationship ...
Tommy Emil Dzus, Johaina Sarrage, Hilde Samdal, François Montastruc, Elena Rocca   +4 more
wiley   +1 more source

Knowledge, attitude, and practices toward pharmacovigilance among undergraduate medical students in a South Indian tertiary care hospital

National Journal of Physiology, Pharmacy and Pharmacology
Background: The adequate knowledge, attitude, and practice (KAP) of pharmacovigilance and adverse drug reactions (ADRs) reporting is essential for undergraduate medical students.
Narasimha Rao A P, Lakshmi S, Vurimi Bhopal Chandra, Anjani Devi Nelavala   +3 more
doaj   +1 more source

Knowledge, Attitudes, Practices and Barriers regarding pharmaco-vigilance among Healthcare Professionals: a cross-sectional study at EHU Oran, Algeria [PDF]

Batna Journal of Medical Sciences
Objective: Adverse drug reactions (ADR) are a major public health issue, emphasizing the need for effective pharmacovigilance practices. This study aims to assess healthcare professionals' knowledge, attitudes, and practices (KAP) regarding ADR ...
Fatima Zohra Nadjet MEKAOUCHE, Fairouz HAOUATTI, Abdessamad DALI-ALI, Abir TACHMA, Amine SMAIL, Habiba FETATI, Asmaa MEMOU, Fatma BOUDIA, Houari TOUMI   +8 more
doaj   +1 more source

Applying machine learning to pharmacovigilance data: A proof‐of‐concept study

British Journal of Clinical Pharmacology, EarlyView.
Aim Machine learning (ML) applications in pharmacovigilance remain limited and underexplored. Using data from the French National pharmacovigilance database (FNPV), this proof‐of‐concept study aimed to assess the feasibility of using a ML algorithm—eXtreme Gradient Boosting (XGBoost)—combined with SHapley Additive exPlanations (SHAP) analysis, to ...
Romain Barus, Pauline Schiro, Jean‐Luc Faillie, Romane Freppel, Johana Béné, Claire de Canecaude, François Montastruc   +6 more
wiley   +1 more source

P1591Cardiovascular toxicity of ibrutinib: a pharmacovigilance study

European Heart Journal, 2019
Abstract Importance Ibrutinib, a first in class Bruton tyrosine kinase inhibitor, has revolutionized treatment for several B-cell malignancies. However, early data suggested that ibrutinib was associated with supra-ventricular arrhythmias (SVA) and bleeding.
J E Salem, A Manouchehri, M arie Bretagne, B Lebrun Vignes, J D Groarke, D B Johnson, T Yang, N M Reddy, C Funck-Brentano, J R Brown, D M Roden, J J Moslehi   +11 more
openaire   +1 more source

A descriptive case series of hepatotoxicity associated with CFTR modulators and possible relevance of pharmacogenetic polymorphisms in cystic fibrosis patients

British Journal of Clinical Pharmacology, EarlyView.
Cystic fibrosis transmembrane conductance regulator (CFTR) modulators are widely used in patients with cystic fibrosis and significantly improve respiratory function and quality of life. However, their effectiveness may be limited by liver damage, which sometimes leads to treatment discontinuation, and the mechanisms underlying this remain poorly ...
Clara Laffitte Redondo, Venceslas Bourdin, Abd El Kader Ait Tayeb, Sihem Benaboud, Inès Martins, Caroline Joyau, Myriam Benhamida, Isabelle Sermet‐Gaudelus, Clémence Martin, Pierre Régis Burgel, Céline Verstuyft, Laurent Chouchana, Estelle Ayme‐Dietrich   +12 more
wiley   +1 more source

Cardiovascular and neuropsychiatric outcomes with PCSK9 inhibitors in atherosclerotic cardiovascular disease: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Study design and main findings. After 1:1 propensity score matching, 60 885 PCSK9 inhibitor users and 60 885 statin‐only users with ASCVD were compared. Kaplan–Meier curves show 12‐month cumulative event‐free survival for MACE, psychiatric disease, and neurodegenerative disease.
Tianshu Gu, Yang Chen, Nan Zhang, Uazman Alam, Riccardo Proietti, Tong Liu, Kang‐Yin Chen, Gregory Y. H. Lip   +7 more
wiley   +1 more source