Results 131 to 140 of about 37,908 (274)

Oligopeptides/DNA Coacervate Droplets as Macromolecular Delivery Microcarriers

Advanced Science, EarlyView.
Oligopeptide–DNA coacervates formed via liquid–liquid phase separation serve as programmable carriers for macromolecular cargos, entering cells through lipid raft–associated pathways and subsequently undergoing enzyme triggered intracellular disassembly driven by DNA degradation processes, thereby enabling efficient, controlled, and spatially defined ...
Linyi Zhang, Chong Wang, Mengqi Han, Yi Yang, Teng Ma, Luoran Shang   +5 more
wiley   +1 more source

Fluvoxamine and lycopene alleviate cisplatin-induced kidney fibrosis by modulating miR-21 and fibrotic signaling pathways

Scientific Reports
Cisplatin (Cis) is a widely utilized chemotherapy drug for managing various cancers, but its efficacy is limited by nephrotoxicity, which frequently results in kidney fibrosis.
Sally E. Abu-Risha, Samia S. Sokar, Mai A. Mousa, Nagla A. El-Shitany, Alaa E. Elsisi   +4 more
doaj   +1 more source

PancDS in Real‐World Practice: A Prospective Multicenter Validation of a Clinical Decision‐Support System Bridging Experience Gaps in Pancreatic Lesion Diagnosis

Advanced Science, EarlyView.
A biomimetic artificial intelligence system, PancDS, has been developed to distinguish pancreatic ductal adenocarcinoma from mass‐forming pancreatitis by adaptively integrating clinical data, radiomics, and deep learning features. Validated across multicenter, reader‐study, and prospective settings, PancDS improves diagnostic accuracy, particularly for
Zhibo Wang, Weinuo Qu, Wenwen Cai, Chuhuai Wang, Chenxi Lyu, Qingguo Xie, Qian Chu, Yaqi Shen, Peng Xiao, Feng Li, Qingpeng Zhang, Jiali Li, Jeong Min Lee, Zhen Li   +13 more
wiley   +1 more source

Scientific Profile of Pharmacology, Toxicology and Pharmaceutics Fields in Middle East Countries: Impacts of Iranian Scientists [PDF]

, 2011
In the present investigation, a statistical analysis was conducted to evaluate the production of scientific papers in the fields of Pharmacology, Toxicology and Pharmaceutical during a period of 1996-2007.
Biglu, M. H.; Department of Medical Information Science and Technology, School of Advanced Biomedical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran, Omidi, Y.; Research Centre for Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran   +1 more
core  

Autism and α7-nicotinic acetylcholine receptors: new pharmacological and herbal interventions

Future Journal of Pharmaceutical Sciences
Background Autism spectrum disorder (ASD) is a worldwide concern that affects 75 million people globally. ASD is characterized by neurological abnormalities that include impaired social interactions, stereotyped patterns of behavior, and cognitive ...
Nourhan A. Khattab, Aya H. El-Kadem, Nada A. Ashour, Nageh Ahmed El-Mahdy, Nagla A. El-Shitany   +4 more
doaj   +1 more source

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

Advanced Science, EarlyView.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li, Zhonglian Cao, Rongrui Zhou, Xu Cheng, Xiaozhi Hu, Shuwen Xu, Zihan Dou, Ling Du, Dianwen Ju   +8 more
wiley   +1 more source

Influência do tratamento com extrato de Polygala paniculata na doença periodontal em ratos. [PDF]

, 2014
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.A doença periodontal é uma doença inflamatória com grande prevalência em adultos, caracterizada por uma infecção bacteriana crônica presente na estrutura ...
Oliveira, Gustavo Barreto
core  

A Non‐Canonical Core Transcriptional Regulatory Circuit Orchestrates Chromatin Reprogramming to Drive Osimertinib Resistance in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
A non‐canonical core transcriptional regulatory circuit, composed of ID3, SMAD3, and NR2F2, drives Osimertinib resistance in non‐small cell lung cancer through super‐enhancer‐mediated activation of EPAS1, which couples neuroendocrine differentiation with ferroptosis evasion.
Aochu Liu, Zhenguo Liu, Lizhen Jiang, Andong Huang, Xinqing Lin, Xinyue Li, Bingyuan Liu, Shiwen Hu, Qiang Pan, Junjun Huang, Liyuan Yin, Liling Jiang, Wei Yi, Wenjun Mao, Yueyuan Zheng, Xianping Shi   +15 more
wiley   +1 more source

PHARMACY PROFESSOR HONORED WITH NIH GRANT AND APPOINTMENT TO NATIONAL ACADEMY OF SCIENCES COMMITTEE [PDF]

, 1992
An associate professor of pharmacology and toxicology at the University of Utah College of Pharmacy has been honored twice during a three-month period-first, from the National Institutes of Health (NIH) and then, an appointment to a committee of the ...

core  

Adverse Events Following Immunization with Novel Oral Polio Vaccine Type 2, and the Experience and Challenges of Reporting in Sierra Leone [Response to Letter]

Drug, Healthcare and Patient Safety
Fawzi Thomas,1,2 Onome T Abiri,2,3 Joyce M Kallon,4 Desmond Maada Kangbai,4 Thomas A Conteh,1,2 Sally-Mattu Conteh,4 Edna G Samuels,4 Olufunsho Awodele5 1Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, College of Medicine and Allied ...
Thomas F, Abiri OT, Kallon JM, Kangbai DM, Conteh TA, Conteh SM, Samuels EG, Awodele O   +7 more
doaj