Results 221 to 230 of about 1,204,338 (306)

Nuclear Pore Mechanotransduction in Oncology: A Structural Axis of Vulnerability for Targeted Intervention

Advanced Materials, EarlyView.
Cancer‐associated NPC remodeling creates a high‐flux, low‐stringency nuclear state that supports malignant adaptation but increases mechanical fragility. Targeting the FG‐barrier or NPC scaffold may drive mechanostat failure, envelope rupture, DNA damage, and loss of nuclear integrity.
Sílvio Terra Stefanello, Caren Rigon Mizdal, Aline Franzen da Silva, Yun Qian, Wei‐En Yuan, Victor Shahin   +5 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

Advanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian, Xu Wang, Alexis Pacheco Benitez, Erick Guerrero, Yaou Duan, Jingwen Wei, Lukas Farbiak, Daniel J. Siegwart   +7 more
wiley   +1 more source

Decoding Synergistic Pathways in Bimetallic MOFs for Advanced Oxidation Processes

Advanced Materials, EarlyView.
This review presents a unified framework linking metal pairing and framework design with electronic structure, redox cycling, oxidant activation, reactive‐species generation, and catalytic performance across photocatalytic and oxidant‐based BMOF‐AOPs. The resulting design principles guide the development of hydrolytically stable and efficient BMOFs for
Karim El‐Naggar, Huayang Zhang, Shaobin Wang   +2 more
wiley   +1 more source

Section C Examination, November 1931, Written Pharmacy

, 1931
Pharmacy Board of New Zealand
core  

Correction: Sphincter-saving surgery versus abdominoperineal resection in low rectal cancer: the role of indocyanine green fluorescence angiography in surgical decision-making. [PDF]

Front Oncol
Misca MC, Petrea SV, Boanta RD, Aldoescu S, Catrina E, Vilcu ME, Grigorean V, Strambu V, Brezean I.   +8 more
europepmc   +1 more source

Section C Examination, November 1931, Practical Pharmacy

, 1931
Pharmacy Board of New Zealand
core  

Translation, cultural adaptation, and validation of the perceived Artificial Intelligence Literacy Questionnaire-6 (PAILQ-6) in Arabic-speaking pharmacists: A cross-sectional methodological study. [PDF]

Explor Res Clin Soc Pharm
Jairoun AA, Shahwan M, Al-Ghananeem AM, El-Dahiyat F, Jaber AAS, Alorfi NM, Alourfi MM, Aldabbagh A, Aldekhail NM, Alsolami FA.   +9 more
europepmc   +1 more source