Results 31 to 40 of about 52,316 (242)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Pharmacy Matters - October 2021 [PDF]

, 2021
Featured stories: Pharmacy Graduate Students Win AAPS Student Chapter Award, Stellar Student: Hyllore Imeri, Pharmacology Graduate Student Striving for Excellencehttps://egrove.olemiss.edu/pharmacy_newsletters/1101/thumbnail ...
University of Mississippi. School of Pharmacy
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

A pilot programme to teach pharmacology using the i nternational nonproprietary names in a pharmacy school in Spain [PDF]

, 2022
Introduction: In pharmacology lectures, one of the major challenges faced by students is how students can remember an increasing list of a large number of drug names.
Duran, Màrius, Mestres, Concepció, Balocco, Raffaella, Uzman, Nilhan, Hernández Hernández, Marta   +4 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Potential Implications of Hyperoside on Oxidative Stress-Induced Human Diseases: A Comprehensive Review

Journal of Inflammation Research, 2023
Kaiyang Wang,1,* Huhai Zhang,2,* Lie Yuan,3,4 Xiaoli Li,3,4 Yongqing Cai1 1Department of Pharmacy, Daping Hospital, Army Medical University, Chongqing, People’s Republic of China; 2Department of Nephrology, Southwest Hospital, Army Medical ...
Wang K, Zhang H, Yuan L, Li X, Cai Y
doaj  

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

TRADITIONS OF SIENTIFIC SCHOOLS IN THE HISTORY OF SCIENCE DEPARTMENT OF PHARMACOLOGY OF PHARMACEUTICAL FACULTY OF THE I.M. SECHENOV FIRST MOSCOW STATE MEDICAL UNIVERSITY

Сеченовский вестник, 2013
The chair of pharmacology, faculty of pharmacy of the I.M. Sechenov First MSMU formed the Moscow school of teaching pharmacology at the Institute of Pharmacy and Pharmaceutical Institute, is a prestigious scientific pharmaceutical center.
A. A. Svistunov, N. P. Bykov
doaj  

Cover, Content, and Editorial Note from Borneo J Pharm Vol. 2 No. 2 November 2019

Borneo Journal of Pharmacy, 2019
Alhamdulillahirabbil ‘alamin. The next edition of Borneo Journal of Pharmacy (Borneo J Pharm), has been published at November 2019. Starting from this edition, Borneo J Pharm make changes to the template in the article that will be published.
Chief Editor of Borneo J Pharm
doaj   +1 more source