Results 71 to 80 of about 289,721 (318)

The Comparison of Gabapentin and Amitriptilin Effectivity as Pain Therapy in Herniated Nucleus Pulposus [PDF]

open access: yes, 2015
Herniated nucleus pulposus (HNP) is one of peripheral neuropathic pain. Although concensus guidelines for the treatment of neuropathic pain are based on the results of the RCT studies, there are still gaps in the literatures.
Cahyaningsih, I. (Indriastuti)   +2 more
core  

Clinical Outcomes of Patients Within the Rheumatoid Arthritis Care Pathway Cohort at a Tertiary Care Integrated Delivery Network: A Comparison to Usual Care

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to compare clinical outcomes between patients in the Allegheny Health Network rheumatoid arthritis (RA) care pathway and patients receiving usual care. Methods The care pathway initiative implements guideline‐based best practice alongside multidisciplinary team‐based care.
Tarun Sharma   +7 more
wiley   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner   +14 more
wiley   +1 more source

Chemical and biological investigations of Delonix regia (Bojer ex Hook.) Raf. [PDF]

open access: yes, 2010
U radu je opisana izolacija pet sastojaka petroleterske i diklormetanske frakcije metanolnog ekstrakta kore biljke Delonix regia: lupeol (1), epilupeol (2), β-sitosterol (3), stigmasterol (4) i p-metoksibenzaldehid (5). Nadalje, testirano je antimikrobno
A. Bauer   +18 more
core   +3 more sources

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

open access: yesAdvanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou   +11 more
wiley   +1 more source

Correction to: Protective Effects of Trigonella foenum graecum L. Extract Against Cytotoxicity Induced by Cyclophosphamide on Ovarian Cancer (SKOV3) and Normal Cell Lines

open access: yesJournal of Mazandaran University of Medical Sciences, 2018
Correction to: Protective Effects of Trigonella foenum graecum L. Extract Against Cytotoxicity Induced by Cyclophosphamide on Ovarian Cancer (SKOV3) and Normal Cell Lines     Mohammad Shokrzadeh1, Emran Habibi2, Niloofar Pourfoladchi3, Hamidreza ...
Mohammad Shokrzadeh   +3 more
doaj  

Unleashing the Power of Machine Learning in Nanomedicine Formulation Development

open access: yesAdvanced Functional Materials, EarlyView.
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore   +7 more
wiley   +1 more source

Portal vein thrombosis in a patient with severe hemophilia B: A challenging balanced management

open access: yesClinical Case Reports
Key Clinical Message The increased life expectancy in patients with hemophilia (PwH) over the last years has raised the incidence of comorbidities, including thromboembolic events.
Olga Benitez‐Hidalgo   +6 more
doaj   +1 more source

Antimicrobial Use and Management of Childhood Diarrhea at Community Drug Retail Outlets in Eastern Ethiopia: A Matched Questionnaire-Based and Simulated Patient-Case Study

open access: yesPediatric Health, Medicine and Therapeutics, 2022
Dumessa Edessa,1 Mekonnen Sisay,2 Bisrat Hagos,3 Firehiwot Amare4 1Department of Clinical Pharmacy, School of Pharmacy, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia; 2Department of Pharmacology and Toxicology, School of ...
Edessa D, Sisay M, Hagos B, Amare F
doaj  

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