Results 131 to 140 of about 736,711 (345)

Reforms in the Holy Infirmary, 1680 [PDF]

, 2007
The Holy Infirmary, at least in theory, bore witness to the very raison d'etre of the Order of St John ­ the care of the infirm. If the knights came to be known as the Hospitallers, it is because the care of the sick became their historical mission ...
Bonello, Giovanni
core  

Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease

Advanced Science, EarlyView.
This study identifies vacuole membrane protein 1 (VMP1) as a critical regulator of intestinal epithelial barrier homeostasis. VMP1 facilitates the recruitment of CORO1C to late endosomes, supporting Retromer‐mediated recycling of the tight junction protein Occludin.
Jiawei Zhao, Jianjun Zou, Chen Zhou, Yingui Wang, Yiman Liu, Yanqing Zhou, Yuxiang Wang, Xinyu Zhang, Huishu Yang, Hongjie Yin, Dongsheng Bai, Yue Zhao, Na Lu   +12 more
wiley   +1 more source

A Mitochondria‐Specific Nanomedicine for Synergistic Chemo‐Photothermal Therapy and Immunogenic Activation Against Breast Cancer

Advanced Science, EarlyView.
Peptide dendrimer–based nanoplatform with mitochondria‐targeting capability was developed for synergistic chemo‐photothermal therapy. The system promotes efficient transcytosis, induces mitochondrial dysfunction, triggers immunogenic cell death (ICD), and enhance antitumor immunity by promoting dendritic cell maturation and T‐cell activation, resulting
Min Li, Jiangqi Feng, Junyang Zhuang, Qingguo Zhong, Yanda Li, Yanzhuo Lv, Shaoteng Huang, Xiangyu Huang, Mingbo Zhang, Xiaofeng Cai, Yuxin Wang, Wenping Chen, Zhenyu Duan, Zhou Chen, Kui Luo, Ning Li   +15 more
wiley   +1 more source

18β‐Glycyrrhetinic Acid and a Nano‐Liposomal Formulation Alleviate Depression‐Like Behaviors via the Microglial mTOR‐Autophagy‐NLRP3 Axis

Advanced Science, EarlyView.
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan, Haitao Yuan, Wenjun Zhu, Xiaokang Xie, Shen Zhou, Wenzhi Hao, Xiaowei Mo, Lian Yang, Xiaojuan Li, Junshan Liu, Lijuan Deng, Jiaxu Chen   +11 more
wiley   +1 more source

Enhanced Photocatalytic Wastewater Purification and Bacterial Elimination via Copper Ion Irradiation‐Induced Modification of BiOCl

Advanced Science, EarlyView.
This study presents a copper ion irradiation method to achieve the modification function of BiOCl. By using high‐energy ion beams to introduce impurity ions inside the material, the intrinsic electric field of BiOCl is optimized, promoting the separation of photogenerated carriers and enhancing the photocatalytic activity.
Sihan Ma, Dewang Cui, Jianglong Kong, Wentao Li, Zheng Han, Yipeng Li, Shidong Zhang, Xinglin Yu, Deng Long, Xue Bai, Lin Wang, Guang Ran, Zhijun Zhao   +12 more
wiley   +1 more source

Managing Medicaid Pharmacy Benefits: Current Issues and Options [PDF]

, 2011
Examines issues and considerations for state reforms of Medicaid prescription drug reimbursement, pharmacy management, and cost sharing and other best practices for realizing ...
Robin Rudowitz, Sandy Kramer, Vernon K. Smith   +2 more
core  

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source

Hospital Pharmacy Service: thinking in the post-pandemic time

Revista Brasileira de Farmácia Hospitalar e Serviços de Saúde, 2020
Angelita C. MELO, Alice R. SILVA, Mario J. SOBREIRA-DA-SILVA, Renata C. NASCIMENTO, Fernando FERNANDEZ-LLIMOS , Antonio M. MENDES, Catarina L. OLIVEIRA , Cesar A. TEIXEIRA , Claudia G. OSORIO-DE-CASTRO , Débora DE CARVALHO , Eugenie D. NERI , Fabio FERRACINI , Javier A. CRIADO , Lucila I. CASTRO-PASTRANA , Luciane F. CALDEIRA, Pamela BERTOLDO , Rodrigo ORELLANA , Selma R. CASTILHO, Simone D. MAHMUD, Teresa HERNÁNDEZ-GALINDO , Valéria S. BEZERRA, Valdjane SALDANHA, Vanusa B. PINTO, Elisangela C. LIMA   +23 more
doaj   +1 more source

“Access to pharmacy services is difficult in China”: a qualitative study from the perspective of transplant recipients to explore their expectations

BMC Health Services Research
Purpose To gain an in-depth and comprehensive understanding of Chinese organ transplant recipients’ perceptions, expectations, and suggestions of pharmacy services to hospital pharmacists.
Zhao Yin, Wan Zhang, Xuedong Jia, Xi Yang, Wenzhi Guo, Hang Fu, Shuzhang Du, Xiaojian Zhang, Fangying Si, Jun Li   +9 more
doaj   +1 more source

Implementation of vertical clinical pharmacist service on venous thromboembolism prophylaxis in hospitalized medical patients

Einstein (São Paulo)
Objective : To describe the vertical clinical pharmacist service’s interventions in prevention of venous thromboembolism. Methods : This prospective study was done at a private hospital.
Celina Setsuko Haga, Cassio Massashi Mancio, Micheline da Costa Pioner, Fabricia Aparecida de Lima Alves, Andreia Ramos Lira, João Severino da Silva, Fábio Teixeira Ferracini, Wladimir Mendes Borges Filho, João Carlos de Campos Guerra, Claudia Regina Laselva   +9 more
doaj   +1 more source