Results 151 to 160 of about 485,652 (302)

First‐line serplulimab plus chemotherapy in extensive‐stage small‐cell lung cancer: Updated results and biomarker analysis from the ASTRUM‐005 randomized clinical trial

Cancer Communications, EarlyView.
Abstract Background The ASTRUM‐005 study previously demonstrated a significant overall survival (OS) benefit with serplulimab (a programmed death 1 inhibitor) plus chemotherapy versus chemotherapy alone in previously untreated extensive‐stage small‐cell lung cancer (ES‐SCLC).
Ying Cheng, Shuang Zhang, Liang Han, Lin Wu, Jun Chen, Peiyan Zhao, Hongmei Sun, Guilan Wen, Yinghua Ji, Anastasia Zimina, Jianhua Shi, Zhijie Pan, Jinsheng Shi, Xicheng Wang, Yuansong Bai, Tamar Melkadze, Yueyin Pan, Xuhong Min, Maksym Viguro, Xingya Li, Yanqiu Zhao, Junquan Yang, Tamta Makharadze, Ekaterine Arkania, Haoyu Yu, Jing Li, Fang Yang, Xinyi Yang, Chen Ling, Qingyu Wang, Yongqiang Shan, Jun Zhu, the ASTRUM‐005 Study Group   +32 more
wiley   +1 more source

Correction: Kuo et al. Involvement of HO-1 and Autophagy in the Protective Effect of Magnolol in Hepatic Steatosis-Induced NLRP3 Inflammasome Activation In Vivo and In Vitro. <i>Antioxidants</i> 2020, <i>9</i>, 924. [PDF]

Antioxidants (Basel)
Kuo NC, Huang SY, Yang CY, Shen HH, Lee YM.   +4 more
europepmc   +1 more source

Factors Associated With Burnout Among US Hospital Clinical Pharmacy Practitioners: Results of a Nationwide Pilot Survey

Hospital Pharmacy, 2017
G. M. Jones, Neil A. Roe, L. Louden, C. Tubbs   +3 more
semanticscholar   +1 more source

Associations of body mass index and waist circumference with incidence of overall and of 27 site‐specific cancers: a population‐based retrospective cohort study

Cancer Communications, EarlyView.
Abstract Background Overweight and obesity are known risk factors for cancer. The aim of this study was to investigate associations of body mass index (BMI) and waist circumference (WC) with incidence of 27 site‐specific cancers stratified by sex and menopausal status accounting for non‐linearity.
Seonghye Kim, Bongseong Kim, Kyu‐won Jung, Ga Eun Nam, Wonyoung Jung, Junhee Park, Kyung‐Do Han, Dong Wook Shin   +7 more
wiley   +1 more source

Knowledge, attitudes, and practices of pharmacists on hierarchical management of COPD: a cross-sectional study in Jiangsu Province. [PDF]

Front Med (Lausanne)
Wu Q, Meng Y, Zhang R, Ding Y, Wang Y, Zhang J.   +5 more
europepmc   +1 more source

Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications

Cancer Communications, EarlyView.
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu, Yingqi Zhao, Xin Zhang, Yuanhe Wang, Qiuchen Chen, Mingrong Zhang, Huan Sheng, Yuying Zhang, Jinyu Guo, Jun Li, Yuxuan Fan, Ziqing Wang, Yalun Li, Haoran Wang, Minjie Wei, Xiaoyun Hu, Huizhe Wu   +16 more
wiley   +1 more source

The Clinical Pharmacist-Led Medication Review Service at the Surgical Department: A Feasibility Study. [PDF]

Scand J Caring Sci
Christiansen M, Joensen N, Jacobsen R.
europepmc   +1 more source

Combined Immediate‐Release and Extended‐Release Formulation of Sodium Valproate Provides Stable Plasma Levels for Inhibition of Histone Deacetylation

Clinical Pharmacology in Drug Development, EarlyView.
Abstract A modified controlled‐release sodium valproate formulation (VAL001, test) was compared with an approved enteric‐coated tablet formulation (Absenor, reference). Pharmacokinetics and safety/tolerability were evaluated in healthy subjects to bridge with positive efficacy results from an early‐phase patient trial of valproate in combination with ...
Nikhil Ahuja, Susanna Kääriäinen, Zsófia Lovró, Mia Lundblad, Kristina Drott, Elsa Lilienberg, Marica T. Engström, Karla Saukkonen, Mika Scheinin   +8 more
wiley   +1 more source

What do women want in pharmacy-based HIV prevention services during pregnancy? Developing attributes and levels for a discrete choice experiment in Western Kenya. [PDF]

AIDS Res Ther
Mugambi ML, Dollah A, Ouda R, Oyugi N, Odhiambo BO, Marwa MM, Nyakina J, Kinuthia J, Weiner BJ, John-Stewart G, Barnabas RV, Hauber B.   +11 more
europepmc   +1 more source

Expedited Approval in Oncology: A Study of European Regulators' Perspectives and Trade‐Offs

Clinical Pharmacology &Therapeutics, EarlyView.
The purpose of this study was to describe the perspectives and trade‐offs of EU regulators about expedited approvals for treatments of patients with advanced cancer. The study consisted of a cross‐sectional survey with assessors and experts from the network of the European Medicines Agency (EMA).
Francesco Pignatti, Filip Josephson, Pierre Demolis, Olli Tenhunen, Elias Péan, Douwe Postmus   +5 more
wiley   +1 more source