Results 201 to 210 of about 696,578 (342)

Population pharmacokinetics and dose–response relationships of mitoxantrone in children with acute myeloid leukaemia

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon   +13 more
wiley   +1 more source

Transforming Brain Health With Neurotechnology Convergence (Part II): Intelligent Neurointervention Systems for Neurological Disorders

open access: yesBrain Health, EarlyView.
ABSTRACT Neurological disorders represent a critical domain within global health, necessitating advanced interventions to address complex pathologies such as tumors, functional disorders, and cerebrovascular diseases. Despite the proven benefits of early intervention, current treatment paradigms face significant challenges: (1) limited precision in ...
Qing Ye   +14 more
wiley   +1 more source

NHS Alcohol consumption survey 2009 [PDF]

open access: yes, 2009
Brackstone, J.   +2 more
core  

Recent Insights Into Alzheimer's Disease: Advances in Pathophysiology and Therapeutic Strategies

open access: yesBrain Health, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a complex neurodegenerative disorder driven by interplay among amyloid‐β (Aβ) plaques, tau neurofibrillary tangles, inflammation and comorbid pathologies. Recent advances in biomarkers and therapeutic approvals have reshaped our understanding of its pathophysiology and treatment landscape.
Jiong Shi   +3 more
wiley   +1 more source

Climate Change, Healthcare, and Surgery: An Investigation of the Technology Acceptance Dynamics Among European Surgeons

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT The relationship between climate change (CC) and healthcare is twofold. On one hand, the effects of CC impact the rise and worsening of several diseases and the need for medical and surgical interventions, especially when extreme weather events occur.
Francesca Dal Mas, Maurizio Massaro
wiley   +1 more source

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