Results 71 to 80 of about 736,711 (345)

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Repeat prescribing of medications: a system-centred risk management model for primary care organisations [PDF]

, 2017
Rationale, aims and objectives: Reducing preventable harm from repeat medication prescriptions is a patient safety priority worldwide. In the United Kingdom, repeat prescriptions items issued has doubled in the last 20 years from 5.8 to 13.3 items ...
Bartlett, Stephen, Bowie, Paul, Dinwoodie, Mark, Man, Shu Ling, Price, Julie, Taylor, Kate   +5 more
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Surviving the surge: Evaluation of early impact of COVID-19 on inpatient pharmacy services at a community teaching hospital

American Journal of Health-System Pharmacy, 2020
Purpose The coronavirus disease 2019 (COVID-19) pandemic has presented novel challenges to healthcare systems; however, an analysis of the impact of the pandemic on inpatient pharmacy services has not yet been conducted.
Sean M. McConachie, Dmitriy M. Martirosov, Bryan Wang, Neha Desai, Sabrina Jarjosa, Lama M Hsaiky   +5 more
semanticscholar   +1 more source

Indek Kepuasan Pasien Suatu Rumah Sakit Swasta Di Purwokerto [PDF]

, 2011
Hospital as a health care facility seeks to create quality health care, affordable and increase patient satisfaction. This study aims to identify satisfaction (assessment) to community health services on the installation of inpatient, outpatient ...
Suroso, J. (Jebul)
core  

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Patient safety: analysis of the impact of implementation of automated dispensing cabinets on drug return in an university hospital

Clinical and Biomedical Research, 2018
Introduction: Patient safety and medication errors have received great attention and interest from health institutions. Drug return is a reverse logistics process that requires further analysis, because the delay or failure to return medications can ...
Ana Paula Deliberal, Daniela Vescia Menna Barreto, Camila Pereira Menezes, Denise Bueno   +3 more
doaj   +2 more sources

The effect of an active on-ward participation of hospital pharmacists in Internal Medicine teams on preventable Adverse Drug Events in elderly inpatients: protocol of the WINGS study (Ward-oriented pharmacy in newly admitted geriatric seniors)

BMC Health Services Research, 2011
Background The potential of clinical interventions, aiming at reduction of preventable Adverse Drug Events (preventable ADEs) during hospital stay, have been studied extensively.
Dijkgraaf Marcel G, Kuks Paul F, Arisz Lambertus, Stuijt Clementine C, de Rooij Sophia E, Wierenga Peter C, Klopotowska Joanna E, Lie-A-Huen Loraine, Smorenburg Susanne M   +8 more
doaj   +1 more source

A rapid review and narrative synthesis of hospital to community pharmacy transfer of care services in England.

International Journal of Pharmacy Practice, 2020
OBJECTIVES A new discharge medicines service in England has been proposed for rollout in July 2020. This study aims to appraise the evidence for hospital to community pharmacy referral services in England. A rapid review methodology was adopted, findings
H. Nazar, Clare Howard, Z. Nazar, N. Watson   +3 more
semanticscholar   +1 more source

Kualitas Pelayanan Rawat Inap Rumah Sakit Umum Daerah Mokopido Tolitoli [PDF]

, 2016
This study aims at determining The Quality of Inpatient Services of Mokopido Regional Public Hospital Tolitolii. This study uses a qualitative research method, in which the data and the information were collected by using a Likert scale instrument and ...
Gafar, M. (Masrin)
core   +1 more source