Results 61 to 70 of about 43,538 (309)

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

Barnes Hospital Bulletin [PDF]

open access: yes, 1968
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1047/thumbnail ...

core   +1 more source

The profession of pharmacy technician in the light of the Act on Certain Medical Professions [PDF]

open access: yesFarmacja Polska
The primary aim of health professional regulations is to improve the quality of health services, as well as to increase the level of patient safety. So far, the professions regulated by professional laws were the professions of doctor, dentist, nurse ...
Anna Pilarska-Romanowska   +1 more
doaj   +1 more source

Beyond p‐values: Assessing clinical significance in acupuncture research

open access: yesAdvanced Chinese Medicine, EarlyView.
Abstract In acupuncture randomized controlled trials (RCTs), the proper interpretation of results requires a thorough understanding of key statistical concepts such as p‐value, effect size, and the minimal clinically important difference (MCID). This paper explores the relationships among these metrics and their implications for assessing the clinical ...
Changzhen Gong
wiley   +1 more source

Amyotrophic Lateral Sclerosis as a Multistep Process in the United States: A Population‐Based Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Amyotrophic lateral sclerosis (ALS) is a fatal, progressive neurodegenerative disease that typically results in death within 3–5 years from symptom onset. However, little is known about the environmental exposures, clinical aspects, or social determinants of health factors that may be associated with the disease.
Jasmine Berry   +7 more
wiley   +1 more source

Critical Roles: California's Allied Health Workforce [PDF]

open access: yes, 2011
Outlines strategies for meeting the shortage of non-nursing professionals such as respiratory therapists, including funding health science education, aligning curricula with employers' needs, and offering innovative models for non-traditional ...

core  

Cervical Spinal Cord Magnetization Transfer Ratio and Its Relationship With Clinical Outcomes in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The cervical spinal cord (cSC) is highly relevant to clinical dysfunction in multiple sclerosis (MS) but remains understudied using quantitative magnetic resonance imaging (MRI). We assessed magnetization transfer ratio (MTR), a semi‐quantitative MRI measure sensitive to MS‐related tissue microstructural changes, in the cSC and its ...
Lisa Eunyoung Lee   +26 more
wiley   +1 more source

Barnes Hospital Bulletin [PDF]

open access: yes, 1967
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1019/thumbnail ...

core   +1 more source

Real‐World Comparison of High‐Efficacy Versus Non‐High‐Efficacy Therapies in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choice of the first disease modifying treatment (DMT) in multiple sclerosis (MS) is a topic of great interest, and whether high‐efficacy DMTs should be the first choice remains debated. We compared treatment outcomes (no evidence of disease activity [NEDA] and its components) between treatment‐naïve relapsing–remitting MS (RRMS ...
Sarmad Al‐Araji   +9 more
wiley   +1 more source

Denying Credit: The Failure to Transition Troops to Civilian Employment [PDF]

open access: yes, 2013
Since September 11, 2001, more than 2.5 million veterans have served in Iraq, Afghanistan, or both ("Gulf War II veterans"). It is widely recognized that securing meaningful employment is one of the most important factors determining the success of each ...

core  

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