Results 111 to 120 of about 17,272 (276)

The Causal Relationship between PCSK9 Inhibitors and Malignant Tumors: A Mendelian Randomization Study Based on Drug Targeting

open access: yes
Objective: This study explores the potential causal association between proprotein convertase subtilisin/kexin 9 (PCSK9) inhibitors and tumor development using Mendelian randomization (MR) based on drug targets.
Wenxin Wang   +5 more
core   +1 more source

Family history and the risk of cancer : genetic factors influencing multiple cancer sites

open access: yes, 2014
A number of co-aggregations of cancers at different sites has been reported, including recognized syndromes (e.g., Li-Fraumeni), and aggregations between cancers at breast, stomach and ovary, between cancers at prostate, urinary tract and other sites, as
E. Negri, C. La Vecchia, F. Turati
core   +1 more source

Dysphagia Is Associated With Need for Surgical Voice Restoration in Unilateral Vocal Fold Immobility

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To evaluate the association between patient‐reported dysphagia symptoms, measured by the Eating Assessment Tool‐10 (EAT‐10), and the need for surgical voice restoration in patients with unilateral vocal fold immobility (UVFI). Methods A retrospective chart review was conducted on adult patients (≥ 18 years) diagnosed with UVFI at a ...
Julian Purrinos   +5 more
wiley   +1 more source

Otalgia with a normal ear

open access: yes, 1987
Ear pain is a diagnostic problem when examination of the ear shows no pathology. Referred otalgia may be caused by neoplasms; dental abnormalities or infections; temporomandibular joint dysfunction; sinus, pharyngeal or salivary gland infections ...
De Silva, A, Thaller, S R
core  

Risk Factors for Cutaneous Immune‐Related Adverse Events in the Japanese Population: A Retrospective Single‐Center Cohort Study

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Immune checkpoint inhibitor (ICI)‐driven alterations in the immune system can induce immune‐related adverse events (irAEs). Cutaneous irAEs are notable for being the most common and for their early onset; however, the risk factors underlying their development and severity remain unclear. In this study, we retrospectively analyzed 1224 Japanese
Tomoya Watanabe   +4 more
wiley   +1 more source

A review of the relationship between dimensions of alcohol consumption and the burden of disease: 2026 update including Mendelian randomisation studies

open access: yesAddiction, EarlyView.
Abstract Background and aims Evidence on the causal impact and corresponding risk relationships between dimensions of alcohol consumption and health outcomes continues to evolve, with some contradictory findings across study designs. This review aimed to update current knowledge on causality and risk relationships to inform global and national ...
Sinclair Carr   +5 more
wiley   +1 more source

Validade discriminante do questionário de qualidade de vida da Universidade de Washington no contexto brasileiro Discriminant validity of the University of Washington quality of life questionnaire in the Brazilian context

open access: yesRevista Brasileira de Epidemiologia, 2012
OBJETIVO: Avaliar a validade discriminante do questionário de qualidade de vida da Universidade de Washington para pacientes com câncer de cabeça e pescoço e identificar possíveis fatores sociodemográficos que modifiquem seus resultados.
Fabiana Paula de Andrade   +5 more
doaj  

Delayed reconstruction of pharyngeal and pharyngoesophageal defects in patients with malignant neoplasms of the larynx and laryngopharynx after laryngectomy

open access: yesScience and Innovations in Medicine
Aim of the review – to investigate the current surgical approaches and complications of delayed reconstruction of pharyngeal and pharyngoesophageal defects in patients with malignant neoplasms of the larynx and laryngopharynx after laryngectomy using different reconstructive materials.
Oleg I. Kaganov   +4 more
openaire   +1 more source

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