Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Phase Change Material (PCM) Microcapsules for Thermal Energy Storage
Phase change materials (PCMs) are gaining increasing attention and becoming popular in the thermal energy storage field. Microcapsules enhance thermal and mechanical performance of PCMs used in thermal energy storage by increasing the heat transfer area ...
Guangjian Peng +4 more
doaj +1 more source
A novel top-down fabrication process for Ge2Sb2Te5 phase change material nanowires
A novel e-beam free, top-down spacer etch process was used to fabricate sub-hundred nanometer Ge2Sb2Te5 phase change nanowires. Naowires with a cross-section dimension of 50 nm × 100 nm (width × height) were obtained and phase change functionality ...
Hector, Andrew L. +19 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigation of a thermal storage system based on phase change material: heat transfer and performance characterisation [PDF]
The integration of latent heat storage solutions into modern domestic heating systems has the potential to enhance the overall system performance compared to standard hot-water systems (radiators and tanks) due to augmentation of the stored heat by the ...
Mathie, R, Gupta, A, Markides, CN
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Portable Thermoelectric Power Generator Coupled with Phase Change Material
Solar is the intermittent source of renewable energy and all thermal solar systems having a setback on non-functioning during the night and cloudy environment.
Lim Chong C. +2 more
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Thermal Frequency Reconfigurable Electromagnetic Absorber Using Phase Change Material
In this study, we propose a thermal frequency reconfigurable electromagnetic absorber using germanium telluride (GeTe) phase change material. Thermally-induced phase transition of GeTe from an amorphous high-resistive state to a crystalline low-resistive
Heijun Jeong +4 more
doaj +1 more source
Melting and solidification models and thermal characteristics of microencapsulated phase change materials [PDF]
Microencapsulated phase change material (MPCM) as a new thermal energy storage material and a heat transfer medium have attracted considerable attention in the thermal energy storage field.
Yang, Jia (Researcher in engineering)
core

