Results 131 to 140 of about 15,287,590 (305)

A novel paraffin/expanded perlite composite phase change material for prevention of PCM leakage in cementitious composites

open access: yes, 2015
In this study, a novel thermal energy storage composite was developed by impregnating paraffin into hydrophobic coated expanded perlite (EPO) granules.
Wilson, John   +4 more
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Phase Change, Interphase Coupling, and Multiphase Transport in Porous Structures

open access: yes
Multiphase flows and phase-change phenomena are often encountered in many engineering systems, such as CCUS (carbon capture, utilization, and storage); the exploitation of oil, natural gas, and other underground resources; the utilization of geothermal ...

core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Phase Transition Dynamics of Phase Change Material in the Grille-Capsule Packed Channel

open access: yesChemical Engineering Transactions
Phase change thermal energy storage technology, with its high energy storage density and near-isothermal heat release characteristics, serves as an effective solution to address the intermittency and fluctuation issues in solar energy utilization ...
Haonan Jia   +3 more
doaj  

Synthesis and temperature control performance of TBAB/TBAHSO4 hydrate composite phase change material

open access: yesGongneng cailiao yu qijian xuebao
The cold energy storage technology based on phase change material (PCM) has received a lot of attention for its ability to effectively reduce carbon emissions compared to traditional refrigerated transport methods.
Lianxin LOU   +4 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Preparation and thermodynamics property of microencapsulated inorganic phase change material (MCPCM) by disperse polymerization

open access: yes, 2008
Preparation and thermodynamics property of microencapsulated inorganic phase change material (MCPCM) by disperse ...
徐芬   +4 more
core  

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