Results 91 to 100 of about 3,374,510 (297)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
MODULAR PHASE CHANGE MATERIAL (PCM) THERMAL MANAGEMENT SYSTEMS FOR CYLINDRICAL LI-ION CELLS [PDF]
, 2020 Foo Shen Hwang +6 more
openalex +1 more source
Performance of phase change materials for heat storage thermoelectric harvesting [PDF]
, 2013 A. Elefsiniotis +9 more
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Chalcogenide phase change materials for nanoscale switching
Since the demonstration of threshold switching in chalcogenide alloys over forty five years ago, phase change materials have been extensively investigated for switching and data storage applications.
Gholipour, B. +7 more
core
Manufacturing high purity chalcogenide glass
, 2014 Chalcogenide materials are finding increasing interest as an active material in next generation optical and electronic devices. There wide range of properties, ranging from photosensitivity, ability to host rare earth ions, electrical conductivity, phase
Bastock, P.J. +5 more
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Modeling Mass Transport in LiFePO4 and Other Phase-Change Materials [PDF]
, 2009 Indrajeet V. Thorat, Dean R. Wheeler
openalex +1 more source