Results 61 to 70 of about 1,239,378 (261)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Resonant cavities with phase-changing materials

open access: yesOptics Letters, 2017
Phase changing materials are commonly used for optical switching, limiting, and sensing. In many important cases, the change in the transmission characteristics of the optical material is caused by light-induced heating. We demonstrate that the incorporation of such optical materials in judiciously designed photonic structures can dramatically alter ...
Roney, Thomas   +2 more
openaire   +2 more sources

Reconfigurable infrared hyperbolic metasurfaces using phase change materials

open access: yesNature Communications, 2018
Here, the authors demonstrate that the dispersion of hyperbolic phonon polaritons can be controlled using the permittivity changes inherent in the different phases of phase change materials.
T. G. Folland   +9 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Modeling InSe Phase-change Materials

open access: yesMRS Proceedings, 2003
ABSTRACTThe amorphous structure of InxSey has been studied by a first principles tight-binding molecular dynamics technique using the program package PLATO (Package for Linear-combination of Atomic Type Orbitals). The three-dimensional amorphous structures with different densities were prepared by quick quenching from the liquid phase.
Kohary, K   +3 more
openaire   +2 more sources

Ab Initio Study of Novel Phase‐Change Heterostructures

open access: yesAdvanced Science
Neuromorphic devices constitute a novel approach to computing that takes inspiration from the brain to unify the processing and storage units. Memories based on phase‐change materials (PCMs) are potential candidates for such devices due to their non ...
Riccardo Piombo   +2 more
doaj   +1 more source

Phase change materials for building construction: An overview of nano-/micro-encapsulation

open access: yesNanotechnology Reviews, 2020
Buildings contribute to 40% of total global energy consumption, which is responsible to 38% of greenhouse gas emissions. It is critical to enhance the energy efficiency of buildings to mitigate global warming.
Sivanathan Amende   +6 more
doaj   +1 more source

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