Results 151 to 160 of about 1,239,582 (260)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Designing Natural Rubber Shape Stabilized Phase Change Materials: Impact of Matrix Network on Thermophysical Properties. [PDF]

Molecules
Neira-Viñas M, Candau N, Fernández AI.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

All-photon logic gate calculation based on phase change materials. [PDF]

Nanophotonics
Sun J, Mou J, Gao J, Wang J, Liu Y, Jin W, Zhang Y, Liu L, Li H, Liu Z.   +9 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Mapping electric fields in real nanodevices by operando electron holography [PDF]

BIO Web of Conferences
Gatel Christophe, Zhang Leigeng, Gruel Kilian, Lorut Frédéric, Hÿtch Martin   +4 more
doaj   +1 more source

Spatially-Controlled Planar Guided Crystallization of Low-Loss Phase Change Materials for Programmable Photonics. [PDF]

Adv Mater
Bentata F, Taute A, Laprais C, Orobtchouk R, Kempf E, Gassenq A, Pipon Y, Calvo M, Martinez V, Monfray S, Saint-Girons G, Baboux N, Nguyen HS, Letartre X, Berguiga L, Genevet P, Cueff S.   +16 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A Roadmap for Biomass-Driven Development of Sustainable Phase Change Materials. [PDF]

ChemSusChem
Brzęczek-Szafran A, Gwóźdź M, Brun N, Wysokowski M, Matuszek K.   +4 more
europepmc   +1 more source