Results 101 to 110 of about 14,191,855 (253)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Thermal Energy Storage in Bio-Inspired PCM-Based Systems

open access: yesEnergies
Continuous growth in energy demand is observed throughout the world, with simultaneous rapid consumption of fossil fuels. New effective technologies and systems are needed that allow for a significant increase in the use of renewable energy sources, such
Kinga Pielichowska   +2 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Use of phase change materials in concrete: current challenges

open access: yesRenewable Energy and Environmental Sustainability, 2019
Sustainability awareness in the building industry has increased in recent years, and several initiatives have been developed. One of the areas gaining attention recently is the application of phase change materials (PCMs) in concrete.
Adesina Adeyemi
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Phase-change materials handbook [PDF]

open access: yes, 1972
Handbook describes relationship between phase-change materials and more conventional thermal control techniques and discusses materials' space and terrestrial applications.
Hale, D. V.   +2 more
core  

Electron-deficient multicenter bonding in phase change materials: A chance for reconciliation [PDF]

open access: yes
In the last years, a controversy has been raised regarding the nature of the chemical bond in phase change materials. Two bonding models have claimed to be able to explain their extraordinary properties: the metavalent bonding model and the hypervalent ...
Ángel, Vegas   +3 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Photoelectromagnetic multimode triggered phase change materials for thermotherapy

open access: yesSusMat
Neither pristine phase change materials (PCMs) nor metal‐organic frameworks (MOFs) can be driven by optical/electrical/magnetic triggers for multiple energy conversion and thermal storage, which cannot satisfy the requirements of multi‐scenario ...
Yang Li   +6 more
doaj   +1 more source

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