Results 91 to 100 of about 21,023,140 (292)
An adaptive phase-field method for structural topology optimization
Journal of Computational PhysicsIn this work, we develop an adaptive algorithm for the efficient numerical solution of the minimum compliance problem in topology optimization. The algorithm employs the phase field approximation and continuous density field. The adaptive procedure is driven by two residual type a posteriori error estimators, one for the state variable and the other ...
Bangti Jin +3 more
openaire +2 more sources
Using Phase-Field Modeling With Adaptive Mesh Refinement To Study Elasto-Plastic Effects In Phase Transformations [PDF]
, 2008 This thesis details work done in the development of the phase field model which allows simulation of elasticity with diffuse interfaces and the extension of a thin interface analysis developed by previous authors to study non-dilute ideal alloys ...
Greenwood, Michael
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Athermal resistance to phase interface motion due to precipitates: A phase field study [PDF]
, 2022 Athermal resistance to the motion of a phase interface due to a precipitate is investigated. The coupled phase field and elasticity equations are solved for the phase transformation (PT).
Levitas, Valery, Javanbakht, Mahdi
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
A simple method for fabricating phase-shifted fibre Bragg gratings with flexible choice of centre wavelength [PDF]
, 2009 A simple technique for fabricating phase-shifted fibre Bragg gratings (PSFBGs) without the use of a phase-shifted phase mask is presented. Two, 3-mm long, standard fibre Bragg gratings (FBGs) were inscribed sequentially in singlemode fibre at the same
Ralph P. Tatam +5 more
core +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Modelling of Fatigue Microfracture in Porous Sintered Steel Using a Phase-Field Method. [PDF]
Materials (Basel), 2023 Tomić Z +4 more
europepmc +1 more source
Phase-field modeling for axonal extension of nerve cells
Mechanical Engineering Journal, 2015 In this study, we applied a modified Kobayashi-Warren-Carter (KWC) phase-field model to the neurite growth process. To confirm the applicability of this model, we observed axonal extension of PC-12D cells cultured with nerve growth factor (NGF). Based on
Tomohiro TAKAKI +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source