Results 51 to 60 of about 21,023,140 (292)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Phase-Field Simulation of Bubble Evolution and Heat Transfer in Microchannels Under Subcooled and Saturated Flow Boiling

Engineering Proceedings
This study numerically investigates the growth and dynamics of a single vapor bubble in a rectangular microchannel under subcooled and saturated inlet conditions using the phase-field method coupled with the Lee phase-change model.
Jawed Ahmed Jamali, Ying He
doaj   +1 more source

Modeling Anisotropic Transport in Polycrystalline Battery Materials

Batteries, 2023
Hierarchical structures of many agglomerated primary crystals are often employed as cathode materials, especially for layered-oxide compounds. The anisotropic nature of these materials results in a strong correlation between particle morphology and ion ...
Simon Daubner, Marcel Weichel, Paul W. Hoffrogge, Daniel Schneider, Britta Nestler   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Experimental and Simulation Study on the Effect of Reduction Pretreatment on the Void Healing of Heavy Plate

Metals, 2022
In addition to eliminating voids in a billet, the reduction pretreatment (RP) process can refine the austenite structure after reheating and can deform the residual voids, which affect the void healing behavior during insulation before rolling, and then ...
Zhen Ning, Xue Li, Hongqiang Liu, Qingwu Cai, Wei Yu   +4 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Computation of Optimal Current References for Flux-weakening of Multi-Phase Synchronous Machines [PDF]

, 2012
Multi-phase synchronous machines are more and more used in specific applications where high power density, low bus voltage, wide speed range and fault-tolerant capabilities are required. Due to the high number of degrees of freedom, multi-phase machines
Bassel Aslan, LU, Li, ASLAN, Bassel, Paul Sandulescu, Eric Semail, SANDULESCU, Paul, MEINGUET, Fabien, Li Lu, KESTELYN, Xavier, F. Meinguet, Luc Kobylanski, SEMAIL, Eric, KOBYLANSKI, Luc, Xavier Kestelyn   +13 more
core   +1 more source

Pore-Scale Numerical Simulation of CO₂–Oil Two-Phase Flow: A Multiple-Parameter Analysis Based on Phase-Field Method

Energies, 2022
A deep understanding of the pore-scale fluid flow mechanism during the CO2 flooding process is essential to enhanced oil recovery (EOR) and subsurface CO2 sequestration. Two-phase flow simulations were performed to simulate the CO2 flooding process based
Rui Song, Yu Tang, Yao Wang, Ruiyang Xie, Jianjun Liu   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source