Results 161 to 170 of about 6,203,659 (303)

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Elastically induced phase-shift and birefringence in optical fibers. [PDF]

Open Res Eur
Steininger E, Mieling T, Chruściel PT.
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Mechanism of the AC-Light-Shift-Induced Phase Shift and a DC Compensation Strategy in Bell-Bloom Magnetometers. [PDF]

Sensors (Basel)
Zhang R.
europepmc   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Optimal control strategy of dual active bridge DC-DC converter with combined dual-phase-shift and traditional-phase-shift controls

, 2016
In order to reduce the power losses of the dual active bridge (DAB) DC-DC converter, an optimal control strategy combining dual-phase-shift and traditional-phase-shift controls is proposed.
Wu, J, Shen, Y, Meng, D, Shen, H, ,, Sun, X   +5 more
core  

Real-Time Optical and Acoustic Characterization of Phase-Shift Droplets for Drug-Delivery Applications. [PDF]

ACS Appl Mater Interfaces
Abeid BA, Chan ZQ, Fabiilli ML, Estrada JB, Aliabouzar M.   +4 more
europepmc   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Numerical analysis for four-wave mixing based wavelength conversion of differential phase-shift keying signals

, 2009
We numerically investigate the main constrains for high efficiency wavelength conversion of differential phase-shift keying (DPSK) signals based on four-wave mixing (FWM) in highly nonlinear fiber (HNLF). Using multi-tone pump phase modulation techniques,
Zhang F, Liu YL, Jia L Peking Univ Sch Elect Engn & Comp Sci State Key Lab Adv Opt Commun Syst & Networks Beijing 100871 Peoples R China. E-mail Address: fzhang@pku.edu.cn, Chen ZY, Jia L, Li M   +5 more
core  

Integrated approach for edge coverage enhancement based on IRS phase shift control and AP selection in dense user communication system. [PDF]

Sci Rep
Shrivastava S, Taneja A, Alqahtani N, Alqahtani A.   +3 more
europepmc   +1 more source