Results 41 to 50 of about 22,890 (262)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

A Pulse Width Modulation-Based Sliding Mode Controller for Phase-Shifted Full-Bridge Converter With Diodes in Series on the Lagging Leg

IEEE Access
The typical strategy for the phase-shifted full-bridge (PSFB) converter is to design a linear compensator based on a small-signal model. However, this approach cannot provide a strongly robust output under changing operating conditions or with ...
Changshuo Li, Wei Zhou, Qunhui Yang, Fuwu Ji   +3 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

A Quasi-Resonant ZVZCS Phase-Shifted Full-Bridge Converter with an Active Clamp in the Secondary Side

Energies, 2018
A novel Pulse-Width-Modulation (PWM) quasi-resonant active-clamp phase-shifted full-bridge converter is presented and analyzed in this paper. In the proposed topology, an active-clamp switch and a clamp capacitor that resonates with the leakage ...
Duong Tran, Nam Vu, Woojin Choi
doaj   +1 more source

Soft-Switching Full-Bridge DC-DC Converter with Energy Recovery Capacitor Snubber

Energies, 2023
This paper describes a high-frequency soft-switching dc-dc converter with a simple energy recovery capacitor snubber on the secondary side. The presented dc-dc full-bridge converter with the energy recovery snubber removes the main drawbacks of the ...
Marek Pastor, Milan Lacko, Jaroslav Dudrik, Adrian Marcinek   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Analysis and Control of Input-Parallel Output-Series Based Combined DC/DC Converter With Modified Connection in Output Filter Circuit

IEEE Access, 2019
Input-parallel output-series (IPOS)-based combined converter is usually used in the situation with low input voltage and high output voltage to satisfy the requirements in switch voltage stress reduction and power expansion. In such a system, the voltage
Jiang You, Lianbin Cheng, Bin Fu, Menglu Deng   +3 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Modeling, Analysis, and Control of an Integrated Hybrid Energy Storage System

IEEE Access, 2019
In traditional hybrid energy storage system (HESS), separated bidirectional dc/dc converter is usually used to interface energy storage system with dc bus.
Jiang You, Weiyan Fan, Rong Sun, Bin Fu
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source