Results 61 to 70 of about 4,031,675 (267)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

In-Air Gesture Interaction: Real Time Hand Posture Recognition Using Passive RFID Tags

IEEE Access, 2019
In-air gesture interaction enables a natural communication between a man and a machine with its clear semantics and humane mode of operation. In this paper, we propose a real-time recognition system on multiple gestures in the air.
Kang Cheng, Ning Ye, Reza Malekian, Ruchuan Wang   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Pharmacokinetics and Bioequivalence of Mycophenolate Sodium Enteric-Coated Tablets Under Fasting and Fed Conditions: A Single-Dose, Open-Label, Four-Period Replicated Crossover Study in Healthy Chinese Male Subjects

Drug Design, Development and Therapy
Peiwen Zhang,1,* Mupeng Li,1,* Hao Jiang,2 Fangfang Liu,1 Qian Huang,1 Yangyun Han,1 Lianlian Fan1 1Phase 1 Clinical Trial Center, Deyang People′s Hospital, Deyang, Sichuan, People’s Republic of China; 2Zhejiang Meidishen Biomedical Co ...
Zhang P, Li M, Jiang H, Liu F, Huang Q, Han Y, Fan L   +6 more
doaj  

Spin-3/2 Ising model on a two-layer Bethe lattice with FM/AFM interactions

Condensed Matter Physics, 2009
Two-layer Bethe lattice whose lattice sites are occupied with spin-3/2 atoms is solved exactly by using the recursion relations in a pairwise approach for given coordination numbers q=3,4 and 6 with equal external magnetic fields acting on the layers ...
E. Albayrak, A. Yigit
doaj   +1 more source

Accurate timekeeping is controlled by a cycling activator in Arabidopsis

eLife, 2013
Transcriptional feedback loops are key to circadian clock function in many organisms. Current models of the Arabidopsis circadian network consist of several coupled feedback loops composed almost exclusively of transcriptional repressors.
Polly Yingshan Hsu, Upendra K Devisetty, Stacey L Harmer   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Pharmacokinetics and Safety of HRS-1780 in Renal Impaired Subjects: A Multicenter, Non-Randomized, Open-Label Study

Drug Design, Development and Therapy
Yue Fei,1 Zhihong Xie,2 Yuanyuan Luo,3 Xiaolan Yong,4 Na Li,1 Rong Huang,1 Xiaolin Du,4 Yijing Zhu,4 Dongmei Lan,3 Yang Qi,3 Gang Cheng,1 Quanren Wang,1 Kai Shen1 1Department of Clinical Research, Jiangsu Hengrui Pharmaceuticals, Shanghai, People’s ...
Fei Y, Xie Z, Luo Y, Yong X, Li N, Huang R, Du X, Zhu Y, Lan D, Qi Y, Cheng G, Wang Q, Shen K   +12 more
doaj  

Pharmacokinetic and bioequivalence of two formulations of Valsartan/Amlodipine Tablet(I) in healthy Chinese volunteers: A randomized, three-period, partially replicated crossover study

Scientific Reports
Valsartan/amlodipine combination tablets can exert synergistic antihypertensive effects through different mechanisms, significantly lowering blood pressure while also addressing multiple risk factors and comorbidities in patients.
Yingying Mei, Xu Zuo, Tiandong Zhang, Ziyun Bu, Zhendan Xu   +4 more
doaj   +1 more source