Results 101 to 110 of about 9,048,704 (302)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Phase formation in selected surface-roughened plasma-nitrided 304 austenite stainless steel

open access: yesScience and Technology of Advanced Materials, 2008
Direct current (DC) glow discharge plasma nitriding was carried out on three selected surface-roughened AISI 304 stainless steel samples at 833 K under 4 mbar pressures for 24 h in the presence of N2:H2 gas mixtures of 50 : 50 ratios.
Gajendra Prasad Singh et al
doaj  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

New Analysis Method for Gold Occurrence in Carlin-type Gold Ore

open access: yesYankuang ceshi, 2013
Gold exists in the form of micro-super micro dispersed states in Carlin-type gold ores, which is in the form of rich organic matter. The gold occurrence state cannot be analyzed accurately or at best, can be roughly estimated by using the Mineral ...
SU Xiu-zhu   +5 more
doaj  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Semiquantitative Analysis of Phase Evolution and Viscosity in Perlite

open access: yesInternational Journal of Ceramic Engineering & Science
Perlite is a noncrystalline volcanic rock with rhyolitic composition that expands four to 20 times its original volume when heated, forming a porous structure widely used in filtration, catalysis, and construction.
Danqi Yin   +8 more
doaj   +1 more source

First to Market is not Everything: an Analysis of Preferential Attachment with Fitness [PDF]

open access: yes, 2007
In this paper, we provide a rigorous analysis of preferential attachment with fitness, a random graph model introduced by Bianconi and Barabasi. Depending on the shape of the fitness distribution, we observe three distinct phases: a first-mover-advantage
Borgs, Christian   +3 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Expanding the thermodynamical potential and the analysis of the possible phase diagram of deconfinement in FL model

open access: yes, 2011
The deconfinement phase transition is studied in the FL model at finite temperature and chemical potential. At MFT approximation, the phase transition can only be the first order in the whole $\mu-T$ phase plane.
Jia-Rong Li   +4 more
core   +1 more source

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