Results 101 to 110 of about 3,995,176 (315)
Phase-independent rhythmic analysis of genome-wide expression patterns
, 2002 We introduce a model-based analysis technique for extracting and characterizing rhythmic expression pro les from genome-wide DNA microarray hybridization data.
Bruce Randall Donald (5409077) +7 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Effect of Double Ageing Heat Treatment on Microstructure of Cu-Cr-Zr Alloy
Advances in Mechanical and Materials EngineeringIn this study, the Cu-0.78Cr-0.18Zr alloy was investigated for microstructural features in as-forged, aged and double aged conditions. This alloy was characterized by optical emission spectroscopy (OES), optical microscopy (OM), scanning electron ...
Muhammad Owais Mirza +1 more
doaj +1 more source
The new phase of transcriptome analysis.
SEIBUTSU BUTSURI KAGAKU, 2006 The FANTOM Consortium analyzed over 2 million sequences of RNAs produced from the mouse genome, obtaining more than 100, 000 full length copies of these RNAs, and used several new technologies to generate more than 20 million tags representing their starts and ends in a technical tour-de-force that provides a amazing new view of our genome.
openaire +3 more sources
Single-Trial Phase Precession in the Hippocampus [PDF]
, 2009 During the crossing of the place field of a pyramidal cell in the rat hippocampus, the firing phase of the cell decreases with respect to the local theta rhythm.
Schmidt, Robert C. +11 more
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Fast and robust three-dimensional best path phase unwrapping algorithm [PDF]
, 2007 What we believe to be a novel three-dimensional (3D) phase unwrapping algorithm is proposed to unwrap 3D wrapped-phase volumes. It depends on a quality map to unwrap the most reliable voxels first and the least reliable voxels last.
Moore, Christopher J. +5 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Modelling phase change in a 3D thermal transient analysis
, 2014 A 3D thermal transient analysis of a gap profiling technique which utilises phase change material (plasticine) is conducted in ANSYS. Phase change is modelled by assigning enthalpy of fusion over a wide temperature range based on Differential Scanning ...
Haque, EEU, Hampson, PR
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source