Results 71 to 80 of about 34,631,452 (311)

Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1/2 clinical trials

The Lancet Oncology, 2020
Summary Background The selective TRK inhibitor larotrectinib was approved for paediatric and adult patients with advanced TRK fusion-positive solid tumours based on a primary analysis set of 55 patients.
D. Hong, S. DuBois, S. Kummar, A. Farago, C. Albert, K. Rohrberg, C. van Tilburg, R. Nagasubramanian, J. Berlin, N. Federman, L. Mascarenhas, B. Geoerger, A. Dowlati, A. Pappo, S. Bielack, F. Doz, R. McDermott, J. Patel, R. Schilder, M. Tahara, S. Pfister, O. Witt, M. Ladanyi, E. Rudzinski, S. Nanda, B. Childs, T. Laetsch, D. Hyman, A. Drilon   +28 more
semanticscholar   +1 more source

Ironic Medications: A Narrative‐Based Psycho‐Educational Intervention to Explore Patient–Provider Communication in Adolescents With Haematological Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with haematological malignancies face significant emotional and relational challenges, often accompanied by difficulties in communicating their needs within the healthcare context. To address these issues, a narrative‐based psycho‐educational intervention based on the creation and prescription of Ironic Medications was ...
Marta Stoppa, Elena Pagani Bagliacca, Selena Russo, Giulia Rampoldi, Maria Grazia Strepparava, Adriana Cristina Balduzzi, Andrea Biondi, Marco Spinelli   +7 more
wiley   +1 more source

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source

Intermetallic phases and element distribution in carbon-free PM high-speed steels of the Fe-Co-Mo type

European Journal of Materials
In contrast to classical carbidic high-speed steels, carbon-free grades of the type Fe-Co-Mo(-W) obtain their strength by precipitation hardening through nm-size intermetallic µ phases; for example, (Fe,Co)7Mo6; coa­rser µ phases, in the low µm range ...
Herbert Danninger, Elisabeth Eitenberger, Klaudia Hradil, Magdalena Dlapka   +3 more
doaj   +1 more source

Long‐Term Outcomes of Patients With Relapsed/Refractory Neuroblastoma Treated on ANBL1221: A Report From the Children's Oncology Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Results of COG ANBL1221 changed treatment paradigms for patients with relapsed/refractory neuroblastoma. Chemoimmunotherapy with irinotecan/temozolomide/dinutuximab is now used as both bridge therapy following suboptimal response to induction and as treatment in first relapse.
Elizabeth Sokol, Arlene Naranjo, Lulu Chen, Rajen Mody, Steven G. DuBois, Rochelle Bagatell, Navin Pinto   +6 more
wiley   +1 more source

Structural and Phase Characteristics of LaNi₅-Based Materials Modified with Ti, Mn, and Co

Alloys
In this work, the results of the structural and phase state of LaNi5-based alloys modified with Ti, Mn, and Co elements, obtained by mechanical alloying and subsequent spark plasma sintering, are presented.
Arman Miniyazov, Mazhyn Skakov, Nuriya Mukhamedova, Igor Sokolov, Aisara Sabyrtayeva, Ospan Oken, Riza Zhakiya, Zhanna Ospanova   +7 more
doaj   +1 more source

Effect of Bi2O3 Excess on Morphology and Structure of BiNbO4 Ceramics

Archives of Metallurgy and Materials, 2013
Celem niniejszej pracy było wytworzenie ceramiki BiNbO4 z mieszaniny proszków metodą reakcji w fazie stałej z następu- jącym spiekaniem swobodnym przeprowadzonym w temperaturze Ts =870°C i Ts =910°C.
Czekaj D., Lisińska-Czekaj A., Osińska K., Biernacki K.   +3 more
doaj   +1 more source

Modelling and Analysis of a Three-Phase to Five-Phase Transformer

International Journal of Emerging Electric Power Systems, 2014
Abstract Multi-phase systems are the focus of research in recent times due to their inherent advantages compared to the three-phase counterpart. A lot of research effort has been put to develop commercially feasible multi-phase drive systems.
Khan, M. Rizwan, Alammari, Rashid, Moinoddin, Shaikh, Iqbal, Atif   +3 more
openaire   +3 more sources

BMT4me En Español: Multisite Feasibility and Usability Testing of a Spanish‐Language mHealth Adherence Support App for Spanish‐Speaking Caregivers of Children After Hematopoietic Stem Cell Transplantation and Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens, Madeline R. Peek, Bianca Franklin, Emre Sezgin, Melissa Beauchemin   +4 more
wiley   +1 more source

Measurable Residual Disease Monitoring During Treatment for Pediatric Acute Myeloid Leukemia in First Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen, Kristian Juul Sandahl, Lene Karlsson, Jonas Abrahamsson, Nira Arad‐Cohen, Daniel Cheuk, Barbara De Moerloose, Linda Fogelstrand, Jose Maria Fernandez Navarro, Bianca F. Goemans, Kirsi Jahnukainen, Gertjan Kaspers, Zhanna Kovalova, Monica Cheng Munthe‐Kaas, Ulrika Norén‐Nyström, Josefine Palle, Ramune Pasauliene, Cornelis Jan Pronk, Kadri Saks, Anne Tierens, Henrik Hasle, Kristian Løvvik Juul‐Dam   +21 more
wiley   +1 more source