Results 131 to 140 of about 14,285,590 (338)

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Variable shift work in family medicine residents is associated with a non-dipper pattern and reduced phase angle: possible adaptive blood pressure mechanisms and body composition imbalance

Frontiers in Cardiovascular Medicine
BackgroundShift work is associated with alterations in blood pressure (BP), metabolic changes, and unhealthy lifestyle patterns. However, the relationship between BP and variability in work hours remains poorly understood.
Elías Cardoso-Peña, Elías Cardoso-Peña, José de Jesús Garduño-García, Alejandra Donají Benítez-Arciniega, Martha Beatriz Bustamante-Hernández, Rigoberto Oros-Pantoja, Alexandra E. Soto-Piña   +6 more
doaj   +1 more source

Low Bioelectrical Impedance Phase Angle Is a Significant Risk Factor for Frailty

BioMed Research International, 2019
The phase angle, which is measured via bioelectrical impedance analysis (BIA), is a clinically important bioimpedance parameter used for nutritional assessment and evaluating the risk of various diseases, such as locomotive syndrome (LS).
Satoshi Tanaka, K. Ando, Kazuyoshi Kobayashi, T. Seki, Takashi Hamada, M. Machino, Kyotaro Ota, M. Morozumi, Shunsuke Kanbara, S. Ito, N. Ishiguro, Y. Hasegawa, S. Imagama   +12 more
semanticscholar   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Phase angle as an early-warning indicator of glycaemic control in adults with type 1 diabetes mellitus: a cross-sectional study

Frontiers in Endocrinology
BackgroundFor patients with poor glycemic control of adult type 1 diabetes mellitus (T1DM), in addition to managing blood glucose levels, it is worth exploring further as an early warning indicator of blood glucose control.Methods56 adults with T1DM ...
Lun Zhang, Jiani Zhu, Fan Yang, Tongfen Cui, Xiaoyun Xi, Luying Yang, Ji-Gan Wang, Yunying Cai   +7 more
doaj   +1 more source

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi, Sola Al Ghazal, Salem Hannoun, Medhat A. Siddik, Nour M. Najjar, Jim Dagher, Joseph Abboud, Myriam G. Semaan, Samia J. Khoury   +8 more
wiley   +1 more source

The role of phase angle in the diagnosis of presarcopenia in elderly patients with type 2 diabetes mellitus

Российский журнал гериатрической медицины
The study of age-associated diseases is an integral component of modern medicine. In the conducted study, diagnostic phase angle limits for the detection of presarcopenia in patients with type 2 diabetes mellitus (T2DM) were determined.
R. N. Obedkov, E. I. Dedov, I. G. Pshennikova   +2 more
doaj   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Changes in body water distribution and phase angle following rapid ascent to 3,680 m and their association with acute mountain sickness: a prospective cohort study

Frontiers in Public Health
BackgroundAcute mountain sickness (AMS) is a common pathological response following rapid ascent to high altitude, and its underlying mechanisms remain incompletely understood.
Xianglian Li, Jie He, Jie Zhang, Yaru Li, Yanlin Zhu, Liwen Mo, Yue Cheng, Yue Cheng   +7 more
doaj   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source