Results 81 to 90 of about 14,285,590 (338)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Development and application of the phase-screen seismic modelling code [PDF]

open access: yes, 2009
As a consequence of the aims of this project, this thesis is divided into two distinct sections. Initially, the computationally efficient phase-screen forward modelling technique is extended to allow investigation of non-normal ray paths.
White, James C.
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

The effect of phase angle on crack growth mechanisms under thermo-mechanical fatigue loading

open access: yesInternational Journal of Fatigue, 2020
The current paper describes TMF crack growth behaviour in an advanced nickel-based superalloy. Changes in behaviour are examined which occur as a function of the phase angle between applied stress and temperature. The fractography of the failed specimens
Jonathan Jones   +9 more
semanticscholar   +1 more source

Ultra-small-angle X-ray scattering study of second-phase particles in heat-treated Zircaloy-4

open access: yes, 2015
The ultra-small-angle X-ray scattering (USAXS) technique has been used to investigate and to quantify the morphology and size distribution of second-phase particles in Zircaloy-4 under various heat-treatment conditions.
Daymond, M. R.   +3 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Numerical investigation of boiling [PDF]

open access: yes, 2012
In this work, we study different phenomena that occur during nucleate boiling. We numerically investigate boiling using two phase flow direct numerical simulation based on a level set / Ghost Fluid method.
Sagan, Michaël   +2 more
core  

Table_1_Brazilian Reference Percentiles for Bioimpedance Phase Angle of Healthy Individuals.XLSX

open access: yes, 2022
ObjectivesThe present study was designed to estimate phase angle percentile curves for a broad age range of healthy individuals.MethodsThis is a cross-sectional study of healthy Brazilian individuals aged five to 80.
Eduardo Mundstock (13006059)   +2 more
core   +1 more source

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