Results 151 to 160 of about 3,398,285 (350)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Improving the thermal performance of roof through the integration of certain phase change materials for minimizing the heat transfer in buildings

open access: yesAin Shams Engineering Journal
Unplasticized Polyvinyl Chloride roofing systems through strategic Phase Change Material integration. The experimental design employed two distinct of Phase Change Material with melting points near 45 °C (referred as PCM1) and 55 °C (referred as PCM2 ...
Dachaphon Kealkaew   +2 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Research on Phase Change Cold Storage Materials and Innovative Applications in Air Conditioning Systems

open access: yesEnergies
Phase change cold storage materials are functional materials that rely on the latent heat of phase change to absorb and store cold energy. They have significant advantages in slight temperature differences, cold storage, and heat exchange.
Zhengjing Li, Yishun Sha, Xuelai Zhang
doaj   +1 more source

Effect of Asymmetric Fins on Thermal Performance of Phase Change Material-Based Thermal Energy Storage Unit [PDF]

open access: gold, 2023
Muhammad Shaban   +4 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

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