Results 61 to 70 of about 1,239,209 (262)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Scalability of Phase Change Materials in Nanostructure Template

International Journal of Photoenergy, 2015
The scalability of In2Se3, one of the phase change materials, is investigated. By depositing the material onto a nanopatterned substrate, individual In2Se3 nanoclusters are confined in the nanosize pits with well-defined shape and dimension permitting ...
Wei Zhang, Biyun L. Jackson, Ke Sun, Jae Young Lee, Shyh-Jer Huang, Hsin-Chieh Yu, Sheng-Po Chang, Shoou-Jinn Chang, Ya-Hong Xie   +8 more
doaj   +1 more source

Tunable nanophotonics enabled by chalcogenide phase-change materials

Nanophotonics, 2020
Nanophotonics has garnered intensive attention due to its unique capabilities in molding the flow of light in the subwavelength regime. Metasurfaces (MSs) and photonic integrated circuits (PICs) enable the realization of mass-producible, cost-effective ...
Abdollahramezani Sajjad, Hemmatyar Omid, Taghinejad Hossein, Krasnok Alex, Kiarashinejad Yashar, Zandehshahvar Mohammadreza, Alù Andrea, Adibi Ali   +7 more
doaj   +1 more source

Overview of Phase-Change Materials Based Photonic Devices

IEEE Access, 2020
Non-volatile storage memory is widely considered to be one of the most promising candidates to replace dynamic random access memory and even static random access memory.
Jianmin Wang, Lei Wang, Jun Liu
doaj   +1 more source

Ultra-compact nonvolatile phase shifter based on electrically reprogrammable transparent phase change materials

PhotoniX, 2022
Optical phase shifters constitute the fundamental building blocks that enable programmable photonic integrated circuits (PICs)—the cornerstone of on-chip classical and quantum optical technologies [1, 2].
Carlos Ríos, Qingyang Du, Yifei Zhang, Cosmin-Constantin Popescu, Mikhail Y. Shalaginov, Paul Miller, Christopher Roberts, Myungkoo Kang, Kathleen A. Richardson, Tian Gu, Steven A. Vitale, Juejun Hu   +11 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Reconfigurable infrared hyperbolic metasurfaces using phase change materials

Nature Communications, 2018
Here, the authors demonstrate that the dispersion of hyperbolic phonon polaritons can be controlled using the permittivity changes inherent in the different phases of phase change materials.
T. G. Folland, A. Fali, S. T. White, J. R. Matson, S. Liu, N. A. Aghamiri, J. H. Edgar, R. F. Haglund, Y. Abate, J. D. Caldwell   +9 more
doaj   +1 more source