Results 91 to 100 of about 1,399,039 (262)
Program phase detection and exploitation [PDF]
Proceedings 20th IEEE International Parallel & Distributed Processing Symposium, 2006 Chen Ding 0001 +4 more
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Use of double-phase-sensitive detection to measure DPOAE signals
Archives of Acoustics, 2014 This paper presents a new method of measuring distortion product otoacoustic emissions (DPOAE) induced by a two-tone acoustic wave. The method is based on double-phasesensitive detection whereby it is possible to precisely measure DPOAE signals whose ...
Wojciech Michalski +2 more
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Precise frequency synchronization detection method based on the group quantization stepping law.
PLoS ONE, 2019 A precise frequency synchronization detection method is proposed based on the group quantization steeping law. Based on the different-frequency group quantization phase processing, high-precision frequency synchronization can be achieved by measuring ...
Baoqiang Du, Ran Deng, Xiyan Sun
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Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Detection of a coherent signal of known phase
Information and Control, 1975 A novel algebraic technique is employed to find asymptotic solutions for Helstrom's integral equation for a single-cavity-mode detector of a coherent signal of known phase. At high and low temperatures, the detection probability is related to the fixed false-alarm probability.
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