Results 91 to 100 of about 1,844,634 (338)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

The QCD phase diagram from analytic continuation

open access: yesPhysics Letters B, 2015
We present the crossover line between the quark gluon plasma and the hadron gas phases for small real chemical potentials. First we determine the effect of imaginary values of the chemical potential on the transition temperature using lattice QCD ...
R. Bellwied   +6 more
doaj   +1 more source

Exploring the QCD landscape with high-energy nuclear collisions

open access: yes, 2011
Quantum chromodynamics (QCD) phase diagram is usually plotted as temperature (T) versus the chemical potential associated with the conserved baryon number (\mu_{B}).
  +23 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

The Phase Diagram of Strong Coupling QCD including Gauge Corrections

open access: yes, 2013
The strong coupling limit of lattice QCD with staggered fermions has been studied for decades, both via Monte Carlo and via mean field theory. In this model, the finite density sign problem can be made mild and the full phase diagram can be obtained ...
de Forcrand, Philippe   +3 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Dynamical phase diagram of ultracold Josephson junctions

open access: yesNew Journal of Physics, 2020
We provide a complete study of the phase diagram characterising the distinct dynamical regimes emerging in a three-dimensional Josephson junction in an ultracold quantum gas.
K Xhani   +5 more
doaj   +1 more source

On equilibration and coarsening in the quantum O(N) model at infinite $N$

open access: yes, 2013
The quantum O(N) model in the infinite $N$ limit is a paradigm for symmetry-breaking. Qualitatively, its phase diagram is an excellent guide to the equilibrium physics for more realistic values of $N$ in varying spatial dimensions ($d>1$).
Chandran, Anushya   +3 more
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Phase diagram of polymer electrolyte: (x)(PEO) – ( 1-x)CF3COOLi

open access: yesRevista Facultad de Ingeniería Universidad de Antioquia, 2012
Solid polymer electrolytes based on poly(ethylene oxide) (PEO) and lithium trifluoroacetate (CF3COOLi) were prepared by a solvent casting method by different concentrations of salt.
Miguel Iban Delgado   +2 more
doaj   +3 more sources

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