Results 201 to 210 of about 569,956 (263)

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

Remarkable stability of γ - N 2 and its prevalence in the nitrogen phase diagram. [PDF]

Sci Rep
Yan J, Dalladay-Simpson P, Conway LJ, Gorelli F, Pickard C, Liu XD, Gregoryanz E.   +6 more
europepmc   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Enhancement of superconductivity and phase diagram of Ta-doped Kagome superconductor CsV₃Sb₅. [PDF]

Sci Rep
Liu J, Li Q, Li Y, Fan X, Li J, Zhu P, Deng H, Yin JX, Yang H, Li J, Wen HH, Wang Z.   +11 more
europepmc   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Designing the stripe-ordered cuprate phase diagram through uniaxial-stress. [PDF]

Proc Natl Acad Sci U S A
Guguchia Z, Das D, Simutis G, Adachi T, Küspert J, Kitajima N, Elender M, Grinenko V, Ivashko O, Zimmermann MV, Müller M, Mielke C, Hotz F, Mudry C, Baines C, Bartkowiak M, Shiroka T, Koike Y, Amato A, Hicks CW, Gu GD, Tranquada JM, Klauss HH, Chang JJ, Janoschek M, Luetkens H.   +25 more
europepmc   +1 more source

Network physics of attractive colloidal gels: Resilience, rigidity, and phase diagram. [PDF]

Proc Natl Acad Sci U S A
Nabizadeh M, Nasirian F, Li X, Saraswat Y, Waheibi R, Hsiao LC, Bi D, Ravandi B, Jamali S.   +8 more
europepmc   +1 more source

Evolution of Magnetic Symmetry through the BiFeO₃-Ca₂Fe_4/3W_2/3O₆ Phase Diagram. [PDF]

Inorg Chem
Crawford CA, Surta TW, Daniels LM, Savvin S, Niu H, Alaria J, Claridge JB, Rosseinsky MJ.   +7 more
europepmc   +1 more source