Results 41 to 50 of about 564,349 (198)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

PHASE DIAGRAMS [PDF]

Journal of Chemical Education, 1996
N. A. Gokcen, R. G. Reddy
  +5 more sources

Scaling Analysis and Application: Phase Diagram of Magnetic Nanorings and Elliptical Nanoparticles

, 2008
The magnetic properties of single-domain nanoparticles with different geometric shapes, crystalline anisotropies and lattice structures are investigated.
C. Kittel, G. Barenblatt, K. O’Grady, Noah Bray-Ali, Rohit Singh, Stephan Haas, Wen Zhang   +6 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Thermodynamic properties and phase diagrams of spin-1 quantum Ising systems with three-spin interactions

, 2011
The spin-1 quantum Ising systems with three-spin interactions on two-dimensional triangular lattices are studied by mean-field method. The thermal variations of order parameters and phase diagrams are investigated in detail.
Baxter R. J., Hui Jiang, Xiang-Mu Kong
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Phase diagrams of flux lattices with disorder

, 1996
We review the prediction, made in a previous work [Phys. Rev. B 52 (1995)], that the phase diagram of type II superconductors consists of a topologically ordered Bragg glass phase at low fields undergoing a transition at higher fields into a vortex glass
A. Houghton, A. I. Larkin, B. Khaykovich, D. Carpentier, D. Grier, D. R. Nelson, D. R. Nelson, D. S. Fisher, E. Chudnovsky, E. H. Brandt, E. H. Brandt, E. H. Brandt, E. Zeldov, G. Eilenberger, H. Safar, H. Safar, In H. S. Bokil, J. A. Fendrich, J. Kierfeld, J. P. Bouchaud, J. P. Bouchaud, J. Villain, L. Balents, L. I. Glazman, M. Charalambous, M. Charalambous, M. Feigelman, M. J. P. Gingras, M. P. A. Fisher, N. Chikumoto, P. Berghuis, P. L. Gammel, P. Le Doussal, P. P. Mitra, R. Cubbit, R. Wördenweber, S. E. Korshunov, S. Friemel, S. Friemel, S. Ryu, T. Giamarchi, T. Giamarchi, T. Giamarchi, T. Giamarchi, T. Giamarchi, T. Hwa, T. Nattermann, U. Yaron, V. Hardy, W. Kwok   +49 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

S=1 kagom\'e Ising model with triquadratic interactions, single-ion anisotropy and magnetic field: exact phase diagrams

, 2002
We consider a S=1 kagom\'e Ising model with triquadratic interactions around each triangular face of the kagom\'e lattice, single-ion anisotropy and an applied magnetic field.
Barry, Barry, Baxter, Baxter, Baxter, Blume, Blume, Capel, Capel, Capel, Griffiths, Houtappel, J.H. Barry, K.A. Muttalib, Keskin, Naya, Roger, Sullivan, Wu, Wu   +19 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source