Upper respiratory virome signatures reflect COVID-19 severity and post-recovery shifts. [PDF]
Gosain M +17 more
europepmc +1 more source
Visible light high-resolution imaging system for large aperture telescope by liquid crystal adaptive optics with phase diversity technique. [PDF]
Xu Z +7 more
europepmc +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Entropy-Based Analysis of Emotional Dynamics in Doctor-Patient Co-Decision in Primary Care. [PDF]
Sarango A +6 more
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Development and Evaluation of the 40K Liquid SNP Array for Population Genetic Analysis in Golden Pompano (<i>Trachinotus ovatus</i>). [PDF]
Liu B +7 more
europepmc +1 more source
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
The Team Science Readiness Framework for scientific research collaboration. [PDF]
Kilcullen MP +5 more
europepmc +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Sunn Pest Optimization (SPO): A Phase-Differentiated Bio-Inspired Metaheuristic for Global Optimization with Application to Precision Agriculture Monitoring Networks. [PDF]
Diri S.
europepmc +1 more source

