Results 51 to 60 of about 6,444,341 (242)

Research on Cross-eye Jamming Technique based on Phase Diversity Processing

open access: yesMATEC Web of Conferences, 2016
The cross-eye jamming technique is a common method for monopulse tracking radar, which can cause a displacement towards the wrong direction and result in an angle deception.
Yu Daobin, Wang Hongyan, Wu Yanhong
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

First Edition of Diversity Center Newsletter

open access: yes, 2018
First Diversity Center newsletter, sent out at the beginning of 2018Documents and ...
UW Bothell Diversity Center
core  

Metagenomics reveals functional profiles of gut microbiota during the recovery phase of acute pancreatitis

open access: yesScientific Reports
Gut microbiota play a critical pathogenic role in acute pancreatitis (AP). This study aimed to investigate the composition and function of gut microbiota during the recovery phase of AP.
Xiao Song   +8 more
doaj   +1 more source

Bacterial community changes in strawberry fruits (Fragaria × ananassa variety “Monterey”) from farm field to retail market stands, an indicator of postharvest contamination

open access: yesFrontiers in Microbiology
BackgroundStrawberry (Fragaria × ananassa) fruits are vulnerable to bacterial contamination; some species are pathogenic and can affect human health. Comprehending the bacterial composition and diversity at different ripe stages is a key determinant of ...
Gabriela N. Tenea, Pamela Reyes
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Genomewide Mutational Diversity in Escherichia coli Population Evolving in Prolonged Stationary Phase

open access: yesmSphere, 2017
Prolonged stationary phase is an approximation of natural environments presenting a range of stresses. Survival in prolonged stationary phase requires alternative metabolic pathways for survival.
Savita Chib   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Insights into fungal communities in composts revealed by 454-pyrosequencing: Implications for human health and safety.

open access: yesFrontiers in Microbiology, 2013
Fungal community composition in composts of lignocellulosic wastes was assessed via 454-pyrosequencing of ITS1 libraries derived from the three major composting phases. Ascomycota represented most (93%) of the 27,987 fungal sequences.
Vidya eDe Gannes   +2 more
doaj   +1 more source

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