Results 51 to 60 of about 309,712 (273)

Test–Retest Reliability of Magnetoencephalography Resting-State Functional Connectivity in Schizophrenia

Frontiers in Psychiatry, 2020
The reliability of magnetoencephalography (MEG) resting-state functional connectivity in schizophrenia (SZ) is unknown as previous research has focused on healthy controls (HC). Here, we examined reliability in 26 participants (13-SZ, 13-HC). Eyes opened
Felicha T. Candelaria-Cook, Julia M. Stephen   +1 more
doaj   +1 more source

A Comparative Study of Functional Connectivity Measures for Brain Network Analysis in the Context of AD Detection with EEG

Entropy, 2021
This work addresses brain network analysis considering different clinical severity stages of cognitive dysfunction, based on resting-state electroencephalography (EEG). We use a cohort acquired in real-life clinical conditions, which contains EEG data of
Majd Abazid, Nesma Houmani, Jerome Boudy, Bernadette Dorizzi, Jean Mariani, Kiyoka Kinugawa   +5 more
doaj   +1 more source

Specific patterns of coherence and phase lag index in particular regions as biomarkers of cognitive impairment in Parkinson's disease

Parkinsonism & Related Disorders, 2023
Cognitive impairment is a persistent and increasingly reported symptom of patients with Parkinson's disease (PD), significantly affecting daily functioning quality. This study aims to evaluate the functional connectivity of the brain network in patients with Parkinson's disease with various severities of cognitive decline using quantitative ...
Katarzyna Zawiślak-Fornagiel, Daniel Ledwoń, Monika Bugdol, Patrycja Romaniszyn-Kania, Andrzej Małecki, Agnieszka Gorzkowska, Andrzej W. Mitas   +6 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Machine Learning Approach Involving Functional Connectivity Features to Classify Rest-EEG Psychogenic Non-Epileptic Seizures from Healthy Controls

Sensors, 2021
Until now, clinicians are not able to evaluate the Psychogenic Non-Epileptic Seizures (PNES) from the rest-electroencephalography (EEG) readout. No EEG marker can help differentiate PNES cases from healthy subjects.
Giuseppe Varone, Wadii Boulila, Michele Lo Giudice, Bilel Benjdira, Nadia Mammone, Cosimo Ieracitano, Kia Dashtipour, Sabrina Neri, Sara Gasparini, Francesco Carlo Morabito, Amir Hussain, Umberto Aguglia   +11 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

The Temporal and Spectral Characteristics of "Fast Rise and Exponential Decay" Gamma-Ray Burst Pulses

, 2010
In this paper we have analyzed the temporal and spectral behavior of 52 Fast Rise and Exponential Decay (FRED) pulses in 48 long-duration gamma-ray bursts (GRBs) observed by the CGRO/BATSE, using a pulse model with two shape parameters and the Band model
Borgonovo, Borgonovo, Hakkila, Kocevski, L. M. Fang, L. Ma, Norris, Norris, Peng, Shahmoradi, Stern, X. H. Zhao, X. W. Bi, Y. Y. Bao, Y. Yin, Z. Y. Peng   +15 more
core   +1 more source

Early phase pharmacokinetics but not pharmacodynamics are influenced by propofol infusion rate [PDF]

, 2009
Background: Conventional compartmental pharmacokinetic models wrongly assume instantaneous drug mixing in the central compartment, resulting in a flawed prediction of drug disposition for the first minutes, and the flaw affects pharmacodynamic modeling ...
Hagihira, Satoshi, Kazama, Tomiei, Kira, Marimo, Masui, Kenichi, Mortier, Eric, Struys, Michel   +5 more
core   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Investigation of mixing performance in electro-osmotic micromixers through rigid baffle design and parameter optimization

Scientific Reports
Electro-osmotic micromixers constitute a specialized class of active micromixers that apply alternating current (AC) to electrodes. This methodology promotes the formation of vortical structures within the fluid medium, resulting in a substantial ...
Ali Khoshnod, Reza Shahsavandi, Khashayar Hosseinzadeh   +2 more
doaj   +1 more source