Results 191 to 200 of about 14,990 (227)

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

Advanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu, Zhihao Zhan, Xiaoxiang Pan, Xinyue Zhang, Penggang Liu, Jing Sun, Xiulong Xu   +6 more
wiley   +1 more source

Hemp Seed Protein-Derived Lipase Inhibitory Peptides Attenuate High-Fat Diet-Induced Obesity: Evidence from Intestinal Fat Digestion and Gut-Liver Axis Regulation. [PDF]

Foods
Yin H, Zhu J, Luo R, Zhong Y, Zhao T, Zhang M, Deng Y.   +6 more
europepmc   +1 more source

Donor Extended Blue TADF Dendrimer for High‐Performance Solution‐Processed OLEDs

Advanced Science, EarlyView.
A dendronized MR‐TADF emitter, DOBNA‐SpAc‐DCz, was designed to improve solubility, hole transport, and exciton dynamics for solution‐processed OLEDs. Incorporation of ter(tert‐butylcarbazole) dendrons decreases ΔEST and accelerates RISC, yielding short delayed lifetimes (∼2 µs).
Mahni Fatahi, Yuka Yasuda, Ryo Kondo, Hironori Kaji, Eli Zysman‐Colman   +4 more
wiley   +1 more source

Optical heterostructure in a two-dimensional organic crystal. [PDF]

Nat Commun
Liao K, Zhang J, Yu XL, Xu W, Xia Z, Zhou D, Mao Z, Lv Y, Ming Y, Liu C, Sheng M, Liu K, Zhang Z, Zhu C, Wang X, Zhu C, An Z, Wang L.   +17 more
europepmc   +1 more source

NAD+ Metabolism Licenses Zygotic Genome Activation via PARP7‐Mediated ADP‐Ribosylation of UHRF1 in Mouse Early Embryos

Advanced Science, EarlyView.
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao, Ziqi Zhang, Anqi Chen, Yanbo Liu, Yuling Lin, Lina Yu, Ruixin Shi, Aolei Guo, Yan Mao, Ganggui Lou, Chaojun Li, Luhong Wen, Guijun Yan, Haixiang Sun   +13 more
wiley   +1 more source

Neuronal correlates of spatial memory updating: c-Fos and GAD67 expression in the object-place recognition task. [PDF]

Sci Rep
Polanczyk R, Dimitrov S, Shan X, Born J, Inostroza M.   +4 more
europepmc   +1 more source

Interfacial Water Coordination on Ruthenium Oxide Nanoparticles Confined Within Covalent Organic Framework and Its Effect on Electrochemical Nitrate Reduction

Advanced Science, EarlyView.
We demonstrate how oxygen‐deficient ruthenium oxide (RuOx) nanoparticles confined within covalent organic framework achieve highly efficient nitrate‐to‐ammonia conversion. Strong interaction between RuOx nanoparticles and COF results in modified interfacial hydrogen‐bond water network and adsorption of nitrogenous intermediates.
Yun Li, Xin Zhao, Arsenii S. Portniagin, Yuxuan Wu, Desui Chen, Haochen Liu, Andrey L. Rogach   +6 more
wiley   +1 more source

The mTOR-Dop1a-Agpat2 axis regulates nuclear phospholipid homeostasis. [PDF]

iScience
Ariyama H, Tsukamura A, Miyatake S, Okado S, Itabashi I, Ogura A, Suzuki A, Kurakawa H, Sakaguchi Y, Nakatake Y, Sanada R, Terakado I, Koshimizu E, Mizuguchi T, Hamada K, Ogata K, Nakagawa E, Sakakibara T, Shirai M, Fujihara Y, Ullah M, Quinodoz M, Rivolta C, Khan AG, Khan MN, Ansar M, Gerkes EH, Rinne T, Stegmann APA, Sinnema M, Alghamdi MA, Alharby E, Balahmar RM, Almontashiri NAM, Baer S, Piton A, Curià CD, Mercier S, Cogné B, Yap P, Morita SY, Kakita A, Kato M, Maruo Y, Matsumoto N, Mori M.   +45 more
europepmc   +1 more source

Tuning the size of quantum dots to enhance charge transfer and photocatalytic CO₂ reduction. [PDF]

RSC Adv
Khalid MA, Mubeen M, Hussain MN, Mukhtar M, Iqbal A, Kovalenko SA, Palato S, Kandola BK, Iqbal A.   +8 more
europepmc   +1 more source

Kilogram-scale one-pot synthesis of multicomponent fullerene composites for efficient inverted perovskite solar cells. [PDF]

Nat Commun
Hou E, Cheng S, Kong S, Qiu Y, Chen J, Chen X, Chen S, Xing Y, Yang J, Xie L, Zhao X, Bu T, Wei Z, Tian C.   +13 more
europepmc   +1 more source