Results 141 to 150 of about 812,448 (319)
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
We report the study of magnetic and orbital order in ${{\Pr }_{0.5}}$ ${\text{Ca}_{0.5}}$ ${\text{MnO}_{3}}$ epitaxial thin films grown on ${{({\text{LaAlO}_{3}})}_{0.3}}$ – $({\text{SrAl}_{0.5}}$ ${\text{Ta}_{0.5}}$ ${{\text{O}}_{3}}{{)}_{0.7 ...
H Wadati+9 more
doaj +1 more source
Indirect evidence for the Gouy phase for matter waves [PDF]
We show that the well known geometric phase, the Gouy phase in optics can be defined for matter waves in vacuum as well. In particular we show that the underlying physics for the "matter waves" Gouy phase is the generalized Schroedinger-Robertson uncertainty principle, more specifically, the off diagonal elements of the covariance matrix.
arxiv
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
Phase diagram of dilute cosmic matter
Enhancement of nuclear pasta formation due to multi-nucleus simultaneous collision is presented based on time-dependent density functional calculations with periodic boundary condition.
Iwata Yoritaka
doaj +1 more source
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien+7 more
wiley +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
Lattice-commensurate skyrmion texture in a centrosymmetric breathing kagome magnet
Skyrmion lattices (SkL) in centrosymmetric materials typically have a magnetic period on the nanometer-scale, so that the coupling between magnetic superstructures and the underlying crystal lattice cannot be neglected. We reveal the commensurate locking
Max Hirschberger+17 more
doaj +1 more source
Linking the Gaseous and Condensed Phases of Matter. The Behavior of Slow Electrons [PDF]
James Turner+3 more
openalex +1 more source