Results 41 to 50 of about 517,913 (266)

Advances in nonlinear spectroscopy using phase modulated light fields: prospective applications in perturbative and non-perturbative regimes

open access: yesAdvances in Physics: X, 2022
Since its first implementation in 2006, in fluorescence detected Fourier transform excitation spectroscopy of rubidium atoms, phase modulation is being increasingly used in nonlinear spectroscopy.
Khadga J. Karki, Marcelo F. Ciappina
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Higher-resolution wavefront sensing based on sub-wavefront information extraction

open access: yesFrontiers in Physics
The limited spatial sampling rates of conventional Shack–Hartmann wavefront sensors (SHWFSs) make them unable to sense higher-order wavefront distortion.
Hongli Guan   +25 more
doaj   +1 more source

A Comparative Study of Adaptive Interlimb Coordination Mechanisms for Self-Organized Robot Locomotion

open access: yesFrontiers in Robotics and AI, 2021
Walking animals demonstrate impressive self-organized locomotion and adaptation to body property changes by skillfully manipulating their complicated and redundant musculoskeletal systems.
Tao Sun   +6 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Multifrequency Phase and Modulation Fluorometry [PDF]

open access: yesAnnual Review of Biophysics and Bioengineering, 1984
Ann. Rev. Biophys. Bioeng. 1984. 13: 105-24 MULTIFREQUENCY PHASE AND MODULATION FLUOROMETRY1 Enrico Gratton Department of Physics, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801 David M. Jameson Department of Pharmacology, The University of Texas Health Science Center at Dallas, Dallas, Texas 75235 Robert D.
Gratton, E, Jameson, DM, Hall, RD
openaire   +4 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Laser Self-Mixing Interferometer Based on Multiple Reflections and Phase-Modulation Technique

open access: yesPhotonics, 2022
An improved method combining multiple reflections with the phase-modulation technique (MR-PM) is proposed to construct a self-mixing interferometer with high accuracy.
Xiulin Wang   +4 more
doaj   +1 more source

Deep phase modulation interferometry

open access: yesOptics Express, 2010
We have developed a method to equip homodyne interferometers with the capability to operate with constant high sensitivity over many fringes for continuous real-time tracking. The method can be considered as an extension of the "J_1...J_4" methods, and its enhancement to deliver very sensitive angular measurements through Differential Wavefront Sensing
Heinzel, G.   +5 more
openaire   +4 more sources

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