Results 121 to 130 of about 2,852,312 (350)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Multi-Agent Deep Reinforcement Learning Based Optimizing Joint 3D Trajectories and Phase Shifts in RIS-Assisted UAV-Enabled Wireless Communications

IEEE Open Journal of Vehicular Technology
Unmanned aerial vehicles (UAVs) serve as airborne access points or base stations, delivering network services to the Internet of Things devices (IoTDs) in areas with compromised or absent infrastructure.
Belayneh Abebe Tesfaw, Rong-Terng Juang, Hsin-Piao Lin, Getaneh Berie Tarekegn, Wendenda Nathanael Kabore   +4 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Reformulasi dari solusi -soliton untuk persamaan korteweg-de vries [PDF]

, 2002
Solusi 3-soliton dari persaxnaan Korteweg-de Vries (MI!) dapat diperoleh dengan Metode Hirota. Reformulasi solusi 3-soliton dinyatakan sebagai superposisi solusi masing-masing individu soliton.
Mustikaningsih , Dian
core  

S-wave phase shift in Lambda-pi scattering

, 1994
We calculate the s-wave strong interaction $\Lambda$$\pi$ phase shift at the $\Xi$ mass taking into account contributions from the ${{\frac{1}{2}}}^{-}$ and ${{\frac{3}{2}}}^{-}$ $\Sigma$ resonances.
Alakabha Datta, Donoghue, Gervais, Gervais, He, Jenkins, Lu, Martin, Nath, Pais, Sandip Pakvasa   +10 more
core   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Further Analysis on \sigma-particle Properties

, 1997
In a previous work, we have reanalyzed the I=0 S-wave \pi\pi-scattering phase-shift through a new method of Interfering Breit-Wigner amplitudes, and have shown the existence of a light scalar, \sigma particle, accompanied by a negative "repulsive core ...
Ishida, Muneyuki, Ishida, Shin, Ishida, Taku, Takamatsu, Kunio, Tsuru, Tsuneaki   +4 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Scattering of massive scalars by Schwarzschild black holes [PDF]

, 2011
The Klein-Gordon equation for the wave function of a single massive scalar is written in spherical and parabolic coordinates in the presence of a Schwarzschild background, and some semi-classical techniques for deriving asymptotic results are considered.
Lee, Derek
core