Results 121 to 130 of about 2,809,534 (302)
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Further Analysis on \sigma-particle Properties
In a previous work, we have reanalyzed the I=0 S-wave \pi\pi-scattering phase-shift through a new method of Interfering Breit-Wigner amplitudes, and have shown the existence of a light scalar, \sigma particle, accompanied by a negative "repulsive core ...
Ishida, Muneyuki +4 more
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Transmission Phase Shift of a Quantum Dot with Kondo Correlations
We study the effects of Kondo correlations on the transmission phase shift of a quantum dot in an Aharonov-Bohm ring. We predict in detail how the development of a Kondo resonance should affect the dependence of the phase shift on transport voltage, gate
A. C. Hewson +27 more
core +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Phase shift keyed, pulse code modulated signal synchronizer [PDF]
Signal is demodulated and synchronized by three loop circuits: ''Q'' loop uses quadrature signal to stabilize frequency; ''B'' loop acts on baseboard signal to stabilize phase; and decoding ''I'' loop acts on in-phase signal.
Kobayashi, H. S.
core +1 more source
S-wave phase shift in Lambda-pi scattering
We calculate the s-wave strong interaction $\Lambda$$\pi$ phase shift at the $\Xi$ mass taking into account contributions from the ${{\frac{1}{2}}}^{-}$ and ${{\frac{3}{2}}}^{-}$ $\Sigma$ resonances.
Alakabha Datta +10 more
core +2 more sources
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source

