Results 191 to 200 of about 2,852,312 (350)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Light does not phase shift the circadian clock of subcutaneous adipose tissue in vitro. [PDF]

NPJ Biol Timing Sleep
Edmondson A, Beresford C, Harmsen JF.
europepmc   +1 more source

Impact of Time-Restricted Feeding on Adaptation to a 6-Hour Delay Phase Shift or a 12-Hour Phase Shift in Mice. [PDF]

Nutrients, 2022
Ren B, Huang Y, Zhang J, Li J, Liu Z, Guan Y, Chen L, Yang G.   +7 more
europepmc   +1 more source

A 1-bit superconductive phase shifter in coplanar waveguide at Ka-band.

, 1999
Walter Mycroft
openalex   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

El Niño-driven phase shift to algal dominance on Isla del Caño's coral reefs: implications for urgent restoration. [PDF]

PeerJ
Palmer CV, Rodríguez Esquivel SV, Parker CM.   +2 more
europepmc   +1 more source

Phase shift between joint rotation and actuation reflects dominant forces and predicts muscle activation patterns. [PDF]

PNAS Nexus, 2023
Sutton GP, Szczecinski NS, Quinn RD, Chiel HJ.   +3 more
europepmc   +1 more source

Phase shifting point diffraction interferometer for calibrating optical flats

, 2013
Ogaro Elijah Nyakang’o
openalex   +1 more source

1266. Characterization of Shifts in Minimum Inhibitory Concentrations During Treatment with Cefiderocol or Comparators in the Phase 3 CREDIBLE-CR and APEKS-NP Studies [PDF]

, 2020
Miki Takemura, Yoshinori Yamano, Yuko Matsunaga, Mari Ariyasu, Roger Echols, Tsutae Den Nagata   +5 more
openalex   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source